Results 61 to 70 of about 824 (158)

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Broad evidence of xylazine in the UK illicit drug market beyond heroin supplies: Triangulating from toxicology, drug‐testing and law enforcement

Addiction, Volume 119, Issue 7, Page 1301-1309, July 2024.
Abstract Background and aims Xylazine is a non‐opioid sedative which has spread rapidly throughout the US illicit drug supply. This study aimed to describe the spread of xylazine throughout the UK illicit drug supply. Methods Xylazine detections in human biological samples were collated from toxicology laboratories operating in the United Kingdom with ...
Caroline S. Copeland, Kathleen Rice, Kirsten L. Rock, Simon Hudson, Peter Streete, Alexander J. Lawson, Lewis Couchman, Adam Holland, Stephen Morley   +8 more
wiley   +1 more source

Uji Efek Sedatif Fraksi Etanol Daun Kratom (Mitragyna Speciosa Korth.) Pada Mencit Jantan Galur Balb/c [PDF]

, 2013
Kratom (Mitragyna speciosa Korth.) is one of traditional medical plant that canproduces both stimulant effects (in low doses) and sedative effects (in high doses).
Ridayani, Y. (Yeni)
core   +1 more source

Kratom (Mitragyna speciosa) for pain management: a systematic review of preclinical evidence and limited clinical data

Phytomedicine Plus
Introduction: Kratom (Mitragyna speciosa) has gained attention as a potential analgesic due to its major alkaloid, mitragynine, which exhibits atypical opioid activity with reduced β-arrestin recruitment.
Christrijogo Soemartono Waloejo, Prananda Surya Airlangga, Bambang Pujo Semedi, Anna Surgean Veterini, Kohar Hari Santoso, Moses Glorino Rumambo Pandin, Dedi Susila, Soni Sunarso Sulistiawan, Cornellius Hendra Purnama Aria Sumantrie, Adi Nugraha Dj Anwar, Gusti Pindo Asa Anindito, Rahmat Kukuh Noviandomo, Dian Anggraini Permatasari Musalim, David Setyo Budi   +13 more
doaj   +1 more source

PERSEPSI,KONSUMSI DAN PREFERENSI TEH KRATOM SEBAGAI MINUMAN KESEHATAN DI KOTA PONTIANAK [PDF]

, 2021
Kratom merupakan salah satu tanaman asli Asia Selatan yang telah banyak digunakan oleh masyarakat sebagai ramuan tradisional untuk membantu dalam menunjang stamina dan kesehatan.
Auliasari, Ria, Elyta, Elyta, Nurmainah, Nurmainah   +2 more
core   +1 more source

Effects of Nutrient Fertility on Growth and Alkaloidal Content in Mitragyna speciosa (Kratom)

Frontiers in Plant Science, 2020
Leaves harvested from the Southeast Asian tree Mitragyna speciosa (kratom) have a history of use as a traditional ethnobotanical source of medicine to combat fatigue, improve work productivity, and to reduce opioid-related withdrawal symptoms.
Mengzi Zhang, Abhisheak Sharma, Francisco León, Bonnie Avery, Bonnie Avery, Roger Kjelgren, Christopher R. McCurdy, Christopher R. McCurdy, Brian J. Pearson   +8 more
doaj   +1 more source

MOESM2 of In silico investigation of mitragynine and 7-hydroxymitragynine metabolism

, 2019
Additional file 2. Table S1, Figures S1 and S2 for the molecular structures and energies of reaction.
Limpanuparb, Taweetham, Noorat, Rattha, Tantirungrotechai, Yuthana   +2 more
openaire   +1 more source

A novel mitragynine analog with low-efficacy mu opioid receptor agonism displays antinociception with attenuated adverse effects [PDF]

, 2021
Mitragynine and 7-hydroxymitragynine (7OH) are the major alkaloids mediating the biological actions of the psychoactive plant kratom. To investigate the structure-activity relationships of mitragynine/7OH templates, we diversified the aromatic ring of ...
Bernhard, Sarah M, Chakraborty, Soumen, Che, Tao, Chintala, Satyanarayana M, et al,, Faouzi, Abdelfattah, Jilakara, Rahul, Majumdar, Susruta, Nuthikattu, Nitin   +8 more
core   +1 more source

Phytochemical Characterization of the Leaves of Grown in USA

Natural Product Communications, 2009
Mitragyna speciosa (Rubiaceae) has traditionally been used in the tropical regions of Asia, Africa and Indonesia as a substitute for opium. Indole alkaloids are the most common compounds that have been isolated.
Francisco León, Eman Habib, Jessica E. Adkins, Edward B. Furr, Christopher R. McCurdy, Stephen J. Cutler   +5 more
doaj   +1 more source

Kratom (Mitragyna speciosa): ¿droga emergente o bala mágica? [PDF]

, 2013
En los últimos años, un número indeterminado y creciente de sustancias con actividad psicotrópica están siendo introducidas en contextos recreativos a través del mercado tecnológico que suponen internet y las nuevas tecnologías, tratando de franquear ...
Giner García, Ricardo, López Briz, Eduardo   +1 more
core