Results 171 to 180 of about 115,266,211 (193)

Distribution of regulatory subunits of protein kinase A and A kinase anchor proteins (AKAP 95, 150) in rat pinealocytes

Cell and Tissue Research, 2002
The rat pineal organ is an established model to study signal transduction cascades that are activated by norepinephrine (NE) and cause increases in cAMP levels and stimulation of protein kinase A (PKA). PKA type II catalyzes the phosphorylation of the transcription factor cAMP-response-element-binding protein (CREB) which is essential for the ...
Koch, Marco, Korf, H.-W.
openaire   +3 more sources

AKAP (A-kinase anchoring protein) domains: beads of structure–function on the necklace of G-protein signalling

Biochemical Society Transactions, 2004
AKAPs (A-kinase anchoring proteins) are members of a diverse family of scaffold proteins that minimally possess a characteristic binding domain for the RI/RII regulatory subunit of protein kinase A and play critical roles in establishing spatial constraints for multivalent signalling assemblies.
C C, Malbon, J, Tao, E, Shumay, H-Y, Wang   +3 more
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Molecular Mechanism of Convergent Regulation of Brain Na+ Channels by Protein Kinase C and Protein Kinase A Anchored to AKAP-15

Molecular and Cellular Neuroscience, 2002
Activation of D1-like dopamine (DA) receptors reduces peak Na(+) current in hippocampal neurons voltage-dependent in a manner via phosphorylation of the alpha subunit. This modulation is dependent upon activation of cAMP-dependent protein kinase (PKA) and requires phosphorylation of serine 573 (S573) in the intracellular loop connecting homologous ...
Angela R, Cantrell, Victoria C, Tibbs, Frank H, Yu, Brian J, Murphy, Elizabeth M, Sharp, Yusheng, Qu, William A, Catterall, Todd, Scheuer   +7 more
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The role of A-kinase anchoring proteins (AKaps) in regulating sperm function.

Society of Reproduction and Fertility supplement, 2007
Cyclic AMP (cAMP)-dependent protein kinase (PKA) is a signalling molecule involved in the regulation of many physiological functions including those of cilia and flagella. PKA localizes to specific cellular structures and organelles by binding to AKAP (A-kinase anchoring protein) molecules via interaction with the regulatory subunits (RI and RII) of ...
D W, Carr, A E Hanlon, Newell
openaire   +1 more source

A Kinase Anchoring Protein (AKAP) Interaction and Dimerization of the RIα and RIβ Regulatory Subunits of Protein Kinase A In vivo by the Yeast Two Hybrid System

Journal of Molecular Biology, 2003
Protein kinase A (PKA) regulatory (R) subunits dimerize through an N-terminal motif. Such dimerization is necessary for binding to PKA anchoring proteins (AKAPs) and targeting of PKA to its site of action. In the present study, we used the yeast two-hybrid system as an in vivo bio-reporter assay and analyzed the formation of homo- and heterodimeric ...
Cathrine R, Carlson, Anja, Ruppelt, Kjetil, Taskén   +2 more
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Regulation of Na,K-ATPase by cAMP-Dependent Protein Kinase Anchored on Membrane via A-Kinase Anchoring Protein Subtype, AKAP-150, in Rat Parotid Gland

Annals of the New York Academy of Sciences, 2003
K, Kurihara, N, Nakanishi
exaly   +3 more sources

A-Kinase Anchoring Proteins (AKAPs)

2020
Ryan Walker-Gray, Enno Klussmann
openaire   +1 more source

A-Kinase Anchoring Protein (AKAP)

2012
Graeme K. Carnegie, John D. Scott
openaire   +1 more source

Caractérisation de la protéine AKAP (A-Kinase Anchoring Protein) chez Plasmodium falciparum

Le paludisme est une maladie tropicale due au parasite P. falciparum. Avec le grand nombre de victimes qui lui sont imputées chaque année, cette maladie demeure la plus grande parasitose tropicale et il est primordial de la combattre. Ce combat passe aussi bien par la sensibilisation des populations que par la recherche. Plusieurs échecs thérapeutiques,
openaire   +1 more source

Anchoring of protein kinase A by A-kinase anchoring protein (AKAP) 150 facilitates papsinogen secretion from gastric chief cells

Gastroenterology, 2001
G XIE, J RAUFMAN
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