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AKAPs (A-kinase anchoring proteins) are members of a diverse family of scaffold proteins that minimally possess a characteristic binding domain for the RI/RII regulatory subunit of protein kinase A and play critical roles in establishing spatial constraints for multivalent signalling assemblies.
C C Malbon +3 more
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A-Kinase Anchoring Protein (AKAP) Expression And Function In Human Airway Smooth Muscle (ASM)
Sarah Horvat +5 more
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Molecular and Cellular Neuroscience, 2002
Activation of D1-like dopamine (DA) receptors reduces peak Na(+) current in hippocampal neurons voltage-dependent in a manner via phosphorylation of the alpha subunit. This modulation is dependent upon activation of cAMP-dependent protein kinase (PKA) and requires phosphorylation of serine 573 (S573) in the intracellular loop connecting homologous ...
Angela R, Cantrell +7 more
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Activation of D1-like dopamine (DA) receptors reduces peak Na(+) current in hippocampal neurons voltage-dependent in a manner via phosphorylation of the alpha subunit. This modulation is dependent upon activation of cAMP-dependent protein kinase (PKA) and requires phosphorylation of serine 573 (S573) in the intracellular loop connecting homologous ...
Angela R, Cantrell +7 more
openaire +2 more sources
The role of A-kinase anchoring proteins (AKaps) in regulating sperm function.
Society of Reproduction and Fertility supplement, 2007Cyclic AMP (cAMP)-dependent protein kinase (PKA) is a signalling molecule involved in the regulation of many physiological functions including those of cilia and flagella. PKA localizes to specific cellular structures and organelles by binding to AKAP (A-kinase anchoring protein) molecules via interaction with the regulatory subunits (RI and RII) of ...
D W, Carr, A E Hanlon, Newell
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