Results 91 to 100 of about 2,808,906 (291)
Detecting haplotype-specific transcript variation in long reads with FLAIR2
Genome BiologyBackground RNA-seq has brought forth significant discoveries regarding aberrations in RNA processing, implicating these RNA variants in a variety of diseases.
Alison D. Tang +5 more
doaj +1 more source
The Tragedy of a Cambridge Feminist [PDF]
, 2015 Overview: Stephen Frug sits down at his computer desk on April 4th, 2011. His wife, Sarah, is in the kitchen trying to feed their three year old son and for once, all is quiet.
Lapointe, Ellen
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Systematic identification of edited microRNAs in the human brain [PDF]
, 2012 Adenosine-to-inosine (A-to-I) editing modifies RNA transcripts from their genomic blueprint. A prerequisite for this process is a double-stranded RNA (dsRNA) structure.
Alon, Shahar +8 more
core +1 more source
The evolution and adaptation of A-to-I RNA editing
PLOS Genetics, 2017 Adenosine-to-inosine (A-to-I) RNA editing is an important post-transcriptional modification that affects the information encoded from DNA to RNA to protein. RNA editing can generate a multitude of transcript isoforms and can potentially be used to optimize protein function in response to varying conditions.
Arielle L. Yablonovitch +3 more
openaire +4 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A New S-S' Pair Creation Rate Expression Improving Upon Zener Curves for I-E Plots
, 2006 To simplify phenomenology modeling used for charge density wave (CDW)transport, we apply a wavefunctional formulation of tunneling Hamiltonians to a physical transport problem characterized by a perturbed washboard potential.
A. W. BECKWITH +3 more
core +1 more source
Adaptive evolution of A-to-I auto-editing site in Adar of eusocial insects
BMC GenomicsBackground Adenosine-to-inosine (A-to-I) RNA editing is a co-/post-transcriptional modification introducing A-to-G variations in RNAs. There is extensive discussion on whether the flexibility of RNA editing exerts a proteomic diversification role, or it ...
Caiqing Zheng, Jiyao Liu, Yuange Duan
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source