Results 151 to 160 of about 2,779,849 (194)

Disruption in A-to-I Editing Levels Affects C. elegans Development More Than a Complete Lack of Editing. [PDF]

Cell Rep, 2019
Ganem NS, Ben-Asher N, Manning AC, Deffit SN, Washburn MC, Wheeler EC, Yeo GW, Zgayer OB, Mantsur E, Hundley HA, Lamm AT.   +10 more
europepmc   +1 more source

Structure-mediated modulation of mRNA abundance by A-to-I editing. [PDF]

Nat Commun, 2017
Brümmer A, Yang Y, Chan TW, Xiao X.
europepmc   +1 more source

A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing. [PDF]

Genome Res, 2019
Licht K, Kapoor U, Amman F, Picardi E, Martin D, Bajad P, Jantsch MF.   +6 more
europepmc   +1 more source

Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets. [PDF]

Nucleic Acids Res, 2018
Pinto Y, Buchumenski I, Levanon EY, Eisenberg E.   +3 more
europepmc   +1 more source

A-to-I editing of coding and non-coding RNAs by ADARs. [PDF]

Nat Rev Mol Cell Biol, 2016
Nishikura K.
europepmc   +1 more source

Base-pairing probability in the microRNA stem region affects the binding and editing specificity of human A-to-I editing enzymes ADAR1-p110 and ADAR2. [PDF]

RNA Biol, 2018
Ishiguro S, Galipon J, Ishii R, Suzuki Y, Kondo S, Okada-Hatakeyama M, Tomita M, Ui-Tei K.   +7 more
europepmc   +1 more source

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A-to-I RNA editing — immune protector and transcriptome diversifier

Nature Reviews Genetics, 2018
Modifications of RNA affect its function and stability. RNA editing is unique among these modifications because it not only alters the cellular fate of RNA molecules but also alters their sequence relative to the genome. The most common type of RNA editing is A-to-I editing by double-stranded RNA-specific adenosine deaminase (ADAR) enzymes.
Eli Eisenberg, Erez Y. Levanon
openaire   +5 more sources

A-to-I editing prevents self-RNA sensing

Nature Reviews Molecular Cell Biology, 2022
Leilei Chen
openaire   +4 more sources

Site‐selective versus promiscuous A‐to‐I editing

WIREs RNA, 2011
AbstractRNA editing by adenosine deamination is acting on polymerase II derived transcripts in all metazoans. Adenosine‐to‐inosine (A‐to‐I) editing is mediated by the adenosine deaminase that acts on RNA (ADAR) enzymes. Two types of adenosine to inosine (A‐to‐I) RNA editing have been defined: site selective and hyper‐editing.
Helene, Wahlstedt, Marie, Ohman
openaire   +2 more sources

A-to-I RNA Editing is Induced Upon Hypoxia

Shock, 2011
Regulating gene expression is part of a cell's response to hypoxia. A-to-I RNA editing is an epigenetic phenomenon that can contribute to RNA and protein levels and to isoform diversity. In this study, we identified alterations in the levels of RNA editing following hypoxic stress in three genes: MED13, STAT3, and F11R.
Yael, Nevo-Caspi, Ninette, Amariglio, Gideon, Rechavi, Gideon, Paret   +3 more
openaire   +2 more sources