Results 51 to 60 of about 574,299 (199)

Changes in ADAR RNA editing patterns in CMV and ZIKV congenital infections

BMC Genomics, 2023
Background RNA editing is a process that increases transcriptome diversity, often through Adenosine Deaminases Acting on RNA (ADARs) that catalyze the deamination of adenosine to inosine.
Benjamin Wales-McGrath, Heather Mercer, Helen Piontkivska   +2 more
doaj   +1 more source

Actions of Agonists, Fipronil and Ivermectin on the Predominant In Vivo Splice and Edit Variant (RDLbd, I/V) of the Drosophila GABA Receptor Expressed in Xenopus laevis Oocytes [PDF]

, 2014
Ionotropic GABA receptors are the targets for several classes of insecticides. One of the most widely-studied insect GABA receptors is RDL (resistance to dieldrin), originally isolated from Drosophila melanogaster.
Biggin, P, Buckingham, SD, Lees, K, Musgaard, M, Sattelle, D, Suwanmanee, S   +5 more
core   +7 more sources

ADAR1 A-to-I RNA editing alters codon usage [PDF]

bioRxiv, 2018
AbstractBackgroundFully grown mammalian oocytes and eggs are transcriptionally quiescent, and therefore have a unique RNA environment in which cellular processes depend on post-transcriptional regulation. RNA editing of adenosines into inosines (A-to-I) by adenosine deaminases acting on RNA (ADARs) is a common post-transcriptional gene regulatory ...
Pavla Brachova, Nehemiah S. Alvarez, X. Hong, Kailey A. Vincent, K. Latham, L. Christenson   +5 more
semanticscholar   +2 more sources

RDDpred: a condition-specific RNA-editing prediction model from RNA-seq data [PDF]

, 2016
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give ...
Benjamin Hur, Min-su Kim, Sun Kim
core   +2 more sources

Dynamic temperature-sensitive A-to-I RNA editing in the brain of a heterothermic mammal during hibernation

bioRxiv, 2018
RNA editing diversifies genomically encoded information to expand the complexity of the transcriptome. In ectothermic organisms, including Drosophila and Cephalopoda, where body temperature mirrors ambient temperature, decreases in environmental ...
K. Riemondy, A. Gillen, Emily A. White, Lori K. Bogren, J. Hesselberth, S. Martin   +5 more
semanticscholar   +1 more source

Characterization of RNA Editome in the Mammary Gland of Yaks during the Lactation and Dry Periods

Animals, 2022
The mammary gland is a complicated organ comprising several types of cells, and it undergoes extensive morphogenetic and metabolic changes during the female reproductive cycle.
Xiaoyun Wu, Wondossen Ayalew, Min Chu, Jie Pei, Chunnian Liang, Pengjia Bao, Xian Guo, Ping Yan   +7 more
doaj   +1 more source

Unraveling pleiotropic functions of A-To-I RNA editing in Drosophila [PDF]

Fly, 2010
In metazoan cells, transcripts that fold into double-strand RNA structures are endowed with the capacity to undergo A-to-I RNA editing, during which adenosines are catalytically deaminated to inosines by a class of enzymes known as ADARs (adenosine deaminases acting on RNA).
J. Jepson, R. Reenan
semanticscholar   +3 more sources

RNA editing signature during myeloid leukemia cell differentiation [PDF]

, 2017
Adenosine deaminases acting on RNA (ADARs) are key proteins for hematopoietic stem cell self-renewal and for survival of differentiating progenitor cells. However, their specific role in myeloid cell maturation has been poorly investigated.
A Athanasiadis, A Gallo, AS Shifera, BE Wulff, BJ Liddicoat, BL Bass, C Cenci, C Sundstrom, C Trapnell, C Trapnell, D Laxminarayana, E Picardi, E Picardi, G Camilli, H Aberle, H Li, JB Patterson, JC Hartner, JH Bahn, JM Desterro, Justin M. Thomas, K Nishikura, L Bazak, L Chen, M D'Antonio, M Daigneault, M Higuchi, M Vogler, MA Zipeto, MA Zipeto, N Mannion, N Paz-Yaacov, Q Jiang, Q Wang, Q Wang, R Marcucci, R XuFeng, RA Steinman, RJ Orlowski, S Tomaselli, S Tomaselli, T Hwang, TD Wu, TR Dawson, W Slotkin, Y Li, Y Pinto, YJ Crow, YS Baek   +48 more
core   +2 more sources

Altered A-to-I RNA Editing in Human Embryogenesis

PLoS ONE, 2012
Post-transcriptional events play an important role in human development. The question arises as to whether Adenosine to Inosine RNA editing, catalyzed by the ADAR (Adenosine Deaminase acting on RNA) enzymes, differs in human embryogenesis and in adulthood.
Ronit Shtrichman, Igal Germanguz, Rachel Mandel, Anna Ziskind, Irit Nahor, Michal Safran, Sivan Osenberg, Ofra Sherf, Gideon Rechavi, Joseph Itskovitz-Eldor   +9 more
openaire   +4 more sources

RNA editing regulates insect gamma-aminobutyric acid receptor function and insecticide sensitivity [PDF]

, 2008
A-to-I pre-mRNA editing by adenosine deaminase enzymes has been reported to enhance protein diversity in the nervous system. In Drosophila, the resistance to dieldrin (RDL) gamma-aminobutyric acid (GABA) receptor subunit displays an editing site (R122 ...
A. Hamon, B. Lapied, G. Le Goff, Z. Es-Salah-Lamoureux   +3 more
core   +3 more sources