Results 131 to 140 of about 83,344 (312)
Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder
Journal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley +1 more source
Species Differences in Microsomal Metabolism of Xanthine-Derived A1 Adenosine Receptor Ligands. [PDF]
Pharmaceuticals (Basel), 2021 Schneider D +4 more
europepmc +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Iodine-125-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors
, 1988 Joel Linden +4 more
openalex +1 more source
Dual Inhibition of Ornithine Decarboxylase and A1 Adenosine Receptor Efficiently Suppresses Breast Tumor Cells. [PDF]
Front Oncol, 2021 Ma H, Li Q, Wang J, Pan J, Su Z, Liu S.
europepmc +1 more source
Advanced Science, Volume 13, Issue 7, 3 February 2026.A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi +8 more
wiley +1 more source
The agonist affinity state of A1 adenosine receptors is influenced byprotonation
, 1990 Edmund Hoppe, Martin Reddington
openalex +1 more source