Results 151 to 160 of about 1,574,329 (197)
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Alterations of adenosine A1 receptors in morphine dependence

Brain Research, 1994
The possibility that central adenosine A1 and A2a receptors mediate opiate dependence was examined in morphine-treated mice using radioligand binding methods. Mice treated with morphine for 72 h demonstrated significant increases in naloxone precipitated abstinence behaviors of jumping, wet-dog shakes, teeth chattering, forepaw trends, forepaw tremors ...
G B, Kaplan   +2 more
openaire   +2 more sources

Adenosine receptor modelling. A1/A2a selectivity

European Journal of Medicinal Chemistry, 2006
Three-dimensional models of the A(1) and A(2a) adenosine receptors (AR) were constructed by means of a homology procedure, using bovine rhodopsin as a template. In order to validate the two models, a docking analysis of selective agonists was carried out.
TUCCINARDI, TIZIANO   +4 more
openaire   +3 more sources

Partners for adenosine A1 receptors.

Journal of molecular neuroscience : MN, 2005
G protein-coupled receptors (GPCRs) are targets for therapy in a variety of neurological diseases. Using adenosine A1 receptors (A1Rs) as paradigm of GPCRs, this review focuses on how protein-protein interactions, from monomers to heteromers, can contribute to hormone/neurotransmitter/neuromodulator regulation.
Franco R   +9 more
openaire   +2 more sources

Affinity chromatography in purification of A1 adenosine receptors

Journal of Chromatography A, 1992
Purification of A1 adenosine receptor of rat brain membranes was performed using a newly developed affinity gel employing xanthine amine congener (XAC) as an immobilized ligand. The A1 adenosine receptor was solubilized with digitonin-cholate from brain membranes and then purified by a sequential use of affinity chromatography on XAC-agarose ...
openaire   +2 more sources

A1 Adenosine Receptor: Role in Diabetes and Obesity

2009
Adenosine mediates its diverse effects via four subtypes (A(1), A(2A), A(2B) and A(3)) of G-protein-coupled receptors. The A(1) adenosine receptor (A(1)AR) subtype is the most extensively studied and is well characterized in various organ systems. The A(1)ARs are highly expressed in adipose tissue, and endogenous adenosine has been shown to tonically ...
Arvinder K, Dhalla   +3 more
openaire   +2 more sources

Adenosine A1 Receptors

2010
Jean-Michel Scherrmann   +199 more
openaire   +1 more source

Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity

Cell Metabolism, 2020
Tarja Niemi   +2 more
exaly  

ADENOSINE A1 RECEPTOR AGONISTS

1999
COUSINS RICHARD PETER CHARLES   +3 more
openaire   +6 more sources

Pharmacological targeting of adenosine receptor signaling

Molecular Aspects of Medicine, 2017
Luis Sobrevia   +2 more
exaly  

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