Results 161 to 170 of about 1,621,127 (284)

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

Intracellular mechanosensation in intestinal smooth muscle: Piezo1 complexes amplify signalling beyond the surface

The Journal of Physiology, EarlyView.
Abstract figure legend Mechanosensation is not confined to the cell surface. In intestinal smooth muscle Piezo1 is predominantly intracellular (86%), where it forms a nanoscale (<40 nm) complex at the sarcoplasmic reticulum (SR)–plasma membrane junction. Within this sensor–amplifier–effector axis intra‐Piezo1 is the sensor that detects force at the SR,
Geoanna M. Bautista, Declan Manning, Emily C. Lieu, Stephanie I. Ugochukwu, Collin Matsumoto, Joshua P. Tulman, Miguel Martin‐Aragon Baudel, Nuria Daghbouche‐Rubio, Steven J. McElroy, Sal A. Baker, Manuel F. Navedo, L. Fernando Santana   +11 more
wiley   +1 more source

Labelling of A1 and A3 adenosine receptors with the new selective A1 agonist 2'-Me-CCPA

, 1998
Brain is rich of adenosine receptors. Radiolabelled adenosine receptor agonists such as [3H]N6-cyclohexyladenosine ([3H]CHA) and [3H]phenylisopropyladenosine were largely used for labelling adenosine A1 receptor sites.
AMENTA, Francesco, FRANCHETTI, Palmarisa, CAPPELLACCI, Loredana, P. Barili, GRIFANTINI, Mario   +4 more
core   +1 more source

The Effect of Acute Beetroot Juice and Caffeine Supplementation on Specific Judo Performance During a Simulated Competition Day in Judo Athletes

European Journal of Sport Science, Volume 26, Issue 11, November 2026.
ABSTRACT Beetroot juice (BJ) and caffeine (CAF) are well‐established ergogenic aids for exercise performance. However, little is known about their efficacy and interaction within the specific context of a judo competition day. This study investigated the acute effects of BJ, CAF, and their combination (BJCAF) on judo‐specific performance across a ...
Sefer Karabağ, Heidar Sajedi, Onur Güler, Vahdet Alaeddinoğlu, Ergün Çakır, Davar Khodadadi, Selahattin Akpınar   +6 more
wiley   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan, Rengasamy Balakrishnan, Manivasagam Muthukumaran Tamilarasan, Subasri Pandian   +3 more
wiley   +1 more source

Loss of caveolar A1 adenosine receptor signalling blunts anti-adrenergic control in heart failure. [PDF]

Cardiovasc Res
Mazzola M, Wang H, Lang D, Balycheva M, Bhogal N, Sanchez-Alonso JL, Diakonov I, Lucarelli C, Lai EC, Punjabi PP, Miragoli M, Faggian G, Glukhov AV, Gorelik J.   +13 more
europepmc   +1 more source

Acute Caffeine Intake Does Not Modulate Active or Reactive Inhibition in Non‐Clinical Young Adults, and ADHD Symptoms Do Not Moderate Its Effects

Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 6, November 2026.
ABSTRACT Background Caffeine is consumed for its presumed cognitive benefits, yet controlled studies have repeatedly failed to find effects on inhibitory control. Cross‐sectional work suggests that people with elevated attention‐deficit/hyperactivity disorder (ADHD) symptoms may benefit from chronic, moderate caffeine consumption, but whether acute ...
Ahmet Altınok
wiley   +1 more source

Matrix‐Activated Aptamer Sensors for Human Serum Analysis

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
The sample self‐analyzes: The predominant serum proteins, albumin and immunoglobulin G, were leveraged to activate the response of fluorescent aptamer probes within the biological matrix. The fluorescence‐anisotropy‐based sensing platform demonstrated both performance and consistency for the direct detection of small molecules in serum‐rich samples ...
Amandine Barbaroux, Benoit Chovelon, Emmanuelle Fiore, Sebastien Vezirian, Mickael Henry, Marwa Zoubeidi, Maria C. DeRosa, Corinne Ravelet, Eric Peyrin   +8 more
wiley   +2 more sources

Bezafibrate prolongs hypothermia induced by an A₁ adenosine receptor agonist in CBA/N mice. [PDF]

J Vet Med Sci
Sato-Hashimoto M, Ohnishi H.
europepmc   +1 more source

Adenosine A1 receptor (ADORA1 ) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source