Results 171 to 180 of about 1,621,127 (284)

Should Coffee Consumers Not Have Their Habitual Morning Coffee Before Testing Their Cognitive Functions?

Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 6, November 2026.
ABSTRACT Objective Caffeine could improve cognitive functions, but study protocols usually prohibit drinking coffee before cognitive testing. However, regular coffee consumers may experience withdrawal effects when they cannot drink their habitual coffee, which may impair cognitive performance.
Nikolaos Pitsikas, Duc Truong Nguyen, Arjan Blokland   +2 more
wiley   +1 more source

Structure-based discovery of positive allosteric modulators of the A₁ adenosine receptor. [PDF]

Proc Natl Acad Sci U S A
Nguyen ATN, Panel N, Vo DD, Thai BS, Chia LY, Lu CS, Hellyer SD, Langiu M, Jörg M, Gregory KJ, Kihlberg J, White PJ, Scammells PJ, Christopoulos A, Carlsson J, May LT.   +15 more
europepmc   +1 more source

A2A adenosine receptor-mediated increase in coronary flow in hyperlipidemic APOE–knockout mice

, 2011
Bunyen Teng, S Jamal MustafaDepartment of Physiology and Pharmacology and Center for Cardiovascular and Respiratory Sciences, West Virginia University, Morgantown, WV, USAAbstract: Adenosine-induced coronary vasodilation is predominantly A2A adenosine ...
Mustafa SJ, Teng B
core  

The Efferocytosis‐Driven Macrophage Polarization: A Concerto in the Tumor Immunosuppressive Microenvironment

MedComm, Volume 7, Issue 11, November 2026.
Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen, Chunzhi Wu, Changquan Huang, Hang Zhou   +3 more
wiley   +1 more source

Caffeine Mitigates Adenosine-Mediated Angiogenic Properties of Choroidal Endothelial Cells Through Antagonism of A₁ Adenosine Receptor and PI3K-AKT Axis. [PDF]

Cells
Park S, Song YS, Feng X, Sorenson CM, Sheibani N.   +4 more
europepmc   +1 more source

Erratum: The Effect of A1 Adenosine Receptor in Diabetic Megalin Loss with Caspase-1/IL18 Signaling [Corrigendum]. [PDF]

Diabetes Metab Syndr Obes, 2020
europepmc   +1 more source

The effect of A1 adenosine receptor in diabetic megalin loss with caspase-1/IL18 signaling. [PDF]

Diabetes Metab Syndr Obes, 2019
Tian D, Shi X, Zhao Y, Peng X, Zou L, Xu L, Ma Y, Wen Y, Faulhaber-Walter R, Chen L.   +9 more
europepmc   +1 more source

The Role of Astrocytes in the Inflammatory Response in Neurodiseases

MedComm, Volume 7, Issue 11, November 2026.
Reactive astrocyte‐mediated pathogenic mechanisms in neurodegenerative diseases Schematic representation of key astrocytic pathways contributing to pathology in the pathogenesis of AD, PD, ALS, and HD. In AD, astrocytes exhibit Aβ plaque‐associated activation characterized by GFAP/S100β upregulation, accompanied by impaired EAAT2‐mediated glutamate ...
Shijun Peng, Lepeng Wang, Jia Ouyang, Ruen Liu   +3 more
wiley   +1 more source

Activating A1 adenosine receptor signaling boosts early pulmonary neutrophil recruitment in aged mice in response to Streptococcus pneumoniae infection. [PDF]

Immun Ageing
Simmons SR, Herring SE, Tchalla EYI, Lenhard AP, Bhalla M, Bou Ghanem EN.   +5 more
europepmc   +1 more source

Repeated Caffeine Intake Suppresses Cerebral Grey Matter Responses to Chronic Sleep Restriction in an A ₁ Adenosine Receptor-Dependent Manner

, 2023
Lin Y, Lange D, Baur D, Foerges A, Chu C, Li C, Elmenhorst E, Neumaier B, Bauer A, Aeschbach D, Landolt H, Elmenhorst D.   +11 more
europepmc   +1 more source