Results 81 to 90 of about 10,696 (197)

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher   +12 more
wiley   +1 more source

When AI outputs become documents: Documentation activity in human–AI dialogue

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract Large language models (LLMs) generate texts that increasingly circulate as documents in knowledge infrastructures, yet their documentary status remains theoretically underdetermined. Unlike traditional documents, LLM outputs lack identifiable authorship, stable provenance, or testimonial grounding.
Sascha Donner
wiley   +1 more source

Exploring the potential of ucuúba (Virola surinamensis) seed fat

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Ucuúba (Virola surinamensis) fat is an important income source for Amazonian communities. Local businesses typically process whole seeds for fat extraction; however, seed structural integrity may influence extraction efficiency and fat quality.
Juan David Marmolejo Tascón   +4 more
wiley   +1 more source

Nutraceutical potential of Mesembryanthemum forsskaolii Hochst. ex Bioss.: Insights into its nutritional composition, phytochemical contents, and antioxidant activity

open access: yesOpen Chemistry
Mesembryanthemum forsskaolii Hochst. ex Bioss is a resilient succulent plant in the Aizoaceae family. This plant has been recognized for its nutritional and metabolic benefits, but its potential remains underexplored.
Qahtan Ahmed A., Alatar Abdulrahman A.
doaj   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

open access: yesBMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng   +10 more
wiley   +1 more source

Nano‐networks via reaction‐induced self‐assembly coordinate spatiotemporal multi‐drug delivery for acute kidney injury therapy

open access: yesBMEMat, EarlyView.
Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin   +17 more
wiley   +1 more source

ABTS Announcement [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2016
  +6 more sources

Antioxidant Studies of One Ayurvedic Medicine, Srikhandasavam

open access: yesJournal of Pharmacy and Bioallied Sciences
Background: Shrikhandasavam is a wellknown Ayurvedic medication intended to cure the negative effects of alcohol and other intoxicating drugs, such as hangovers, as well as related issues like as headaches, alcohol intoxication, indigestion, and so on ...
Kondamma Sanapati   +7 more
doaj   +1 more source

Effects of Wheat Bran‐Derived Arabinoxylan Oligosaccharides on Dough and Noodle‐Making Properties

open access: yesCereal Chemistry, EarlyView.
ABSTRACT Background and Objectives This study investigates the structural modifications of arabinoxylan (AX) through enzymatic hydrolysis and evaluates the potential application of arabinoxylan oligosaccharides (AXOS) as functional ingredients in wheat noodles, contrasting their effects with those of native AX.
Yunseo Kim, Meera Kweon
wiley   +1 more source

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