Results 41 to 50 of about 3,425 (149)

Practical Recommendations for Anticoagulation in Patients With Atrial Fibrillation

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Oral anticoagulation (OAC) reduces stroke risk by at least two thirds and mortality by one fourth. The threshold for net clinical benefit of OAC is met when stroke risk exceeds 1%–2% per year. Direct oral anticoagulants (DOACs) are preferred to vitamin K antagonists (VKAs) in most patients, including in the elderly and chronic kidney disease ...
Nicolas Johner, Baris Gencer
wiley   +1 more source

Impact of Atrial Fibrillation on the Risk of Thrombosis and Bleeding for Patients With Polycythemia Vera and Essential Thrombocytosis in the Real World

American Journal of Hematology, Volume 101, Issue 9, Page 2463-2468, September 2026.
Rodrigo Ortega Perez, Luis Manuel Domínguez Rodríguez, Francisca Ferrer‐Marín, Beatriz Cuevas Ruíz, Clara Martínez Valverde, Patricia Vélez Tenza, María Isabel Mata Vázquez, Adrián Segura Díaz, María Laura Fox, Elvira Mora, Manuel Mateo Pérez Encinas, Mercedes Gasior Kabat, Gonzalo Carreño‐Tarragona, Rafael Andrés del Orbe, Gonzalo Caballero‐Navarro, Elena Magro Mazo, Ana Pardo Sanz, José Luis Zamorano Gómez, Alberto Álvarez Larrán, Valentín Garcia‐Gutierrez   +19 more
wiley   +1 more source

Perspectives of Older Patients on the Complexity of Medication Use

Journal of the American Geriatrics Society, Volume 74, Issue 5, Page 1255-1264, May 2026.
ABSTRACT Background Medication use complexity is associated with non‐adherence, hospitalizations, and lower quality of life. It is most frequently measured with the Medication Regimen Complexity Index (MRCI). This instrument estimates the complexity of a patient's medication regimen, taking into account the pharmaceutical dosage forms and routes ...
Charlotte M. Falke, Mariëlle F. J. Koolen, Samuel L. Timmer, Fatma Karapinar‐Çarkit, Marcel L. Bouvy, Antoine C. G. Egberts, Wilma Knol   +6 more
wiley   +1 more source

Efficiency of treatment by acenocoumarol in patients with permanent form of atrial fibrillation, with using models of personalized medicine

RUDN Journal of Medicine, 2009
Acenocoumarol is the global standard of anticoagulant therapy, but often treatment with acenocoumarol accompanied by adverse drug reactions. Model of personalized medicine, actively developing now, can reduce the number of side effects during therapy of ...
I V Kukes, V N Shan
doaj  

Polymorphic Variants in Acenocoumarol-Related Genes CYP2C9 and VKORC1 and Their Frequencies in Bulgarian Population

Acta Medica Bulgarica
Introduction. Acenocoumarol is an indirect anticoagulant, a 4-hydroxycoumarin derivative, which is used in the treatment of various thromboembolic diseases.
Tzveova R., Dimitrova-Karamfilova A., Vandeva S., Atanasov P., Pendicheva-Duhlenska D., Nachev G., Mitev V., Kaneva R.   +7 more
doaj   +1 more source

Conducting Medication Reviews: A Comparative Study Between ChatGPT‐4 and Healthcare Professionals

Journal of the American Geriatrics Society, Volume 74, Issue 5, Page 1378-1385, May 2026.
ABSTRACT Background The increasing prevalence of patients with hyperpolypharmacy (> 10 medications) has made medication reviews increasingly complex. ChatGPT‐4‐Turbo (ChatGPT), a large language model, has demonstrated potential in healthcare applications and could potentially support medication reviews.
Simone M. K. ten Hoope, Sabrina Marongiu, Carl E. H. Siegert, Eibert R. Heerdink, Marjo J. A. Janssen, Fatma Karapinar‐Çarkit   +5 more
wiley   +1 more source

The Association Between Long-Term Acenocoumarol Treatment and Vitamin D Deficiency

Frontiers in Endocrinology, 2018
ObjectiveBoth vitamin D and K2 are involved in a number of metabolic processes, including bone metabolism; however, associations between the vitamins are not fully understood. The aim of the study was to evaluate serum concentrations of 25-hydroxyvitamin
Jolanta Sawicka-Powierza, Jolanta Sawicka-Powierza, Jerzy Konstantynowicz, Ewa Jablonska, Beata Zelazowska-Rutkowska, Wojciech Jelski, Pawel Abramowicz, Caroline Sasinowski, Slawomir Chlabicz   +8 more
doaj   +1 more source

An acenocoumarol dosing algorithm using clinical and pharmacogenetic data in Spanish patients with thromboembolic disease. [PDF]

PLoS ONE, 2012
Appropriate dosing of coumarins is difficult to establish, due to significant inter-individual variability in the dose required to obtain stable anticoagulation. Several genetic and other clinical factors have been associated with the coumarins dose, and
Alberto M Borobia, Rubin Lubomirov, Elena Ramírez, Alicia Lorenzo, Armando Campos, Raul Muñoz-Romo, Carmen Fernández-Capitán, Jesús Frías, Antonio J Carcas   +8 more
doaj   +1 more source

Analysis of acenocoumarol and levofloxacin interaction in elderly institutionalized patients [PDF]

Farmacia Hospitalaria, 2019
Objective: To analyze the interaction between acenocoumarol and levofloxacin in the elderly. We also assessed how hypoalbuminemia affects international normalized ratio variation.
Pilar Taberner-Bonastre , Ana Moreno-Miralles , Isabel Quintana-Vargas , Juan Francisco Peris-Martí   +3 more
doaj   +1 more source

Vascular Reconstruction in Extremity Soft Tissue Sarcomas: A Systematic Review and Single‐Arm Meta‐Analysis

Journal of Surgical Oncology, Volume 133, Issue 4, Page 486-510, March 15, 2026.
ABSTRACT Introduction The management of extremity soft tissue sarcomas (STS) involving major vessels presents unique challenges, historically leading to amputation. Advances in vascular reconstruction have enabled limb‐sparing surgery (LSS), but outcomes and perioperative risks remain uncertain.
Lucas Monteiro Delgado, Bernardo Fontel Pompeu, Vinícius dos Santos Macedo, Gabriel Henrique Acedo Martins, Eric Pasqualotto, Matheus Reginato Araujo, Julia Hoici Brunini, Victor Andrade Nunes, Cláudia Theis, Samuel Aguiar Junior   +9 more
wiley   +1 more source