Results 51 to 60 of about 3,425 (149)

Safety of thrombolysis with IV rt-PA in patients with atrial fibrillation related ischemic strokes and prior subtherapeutic use of coumarinic anticoagulants [PDF]

Romanian Journal of Neurology, 2013
Background and purpose. There are conflicting data in the literature regarding the safety of intravenous thrombolysis in patients with ischemic strokes receiving prior treatment with vitamin K antagonists.
Elena Terecoasa, Cristina Tiu, Jaime Masjuan, Maria Alonso de Lecinana, Gheorghe A. Dan   +4 more
doaj   +1 more source

Neck‐vein thrombosis during spaceflight

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 24-34, January 2026.
Spaceflight imposes unique environmental challenges, including weightlessness, increased radiation exposure and confinement, which can lead to unexpected health effects. One such example is neck‐vein thrombosis, a condition rarely seen on Earth without predisposing factors such as venous catheters or infections.
Ulrich Limper, Jens Jordan
wiley   +1 more source

Establishment of Acenocoumarol Pharmacogenetic Algorithm Including CYP2C9 and VKORC1 Genotypes in Bulgarian Patients Treated with Coumarin Anticoagulants

Acta Medica Bulgarica
Acenocoumarol, a 4-hydroxycoumarin derivative, is widely prescribed for the primary and secondary prevention of thromboembolic disorders. Maintenance dosing of acenocoumarol is significantly influenced by polymorphic variants in the CYP2C9 and VKORC1 ...
Tzveova R., Saraeva R., Dimitrova-Karamfilova A., Nachev G., Mitev V., Kaneva R., Pendicheva-Duhlenska D.   +6 more
doaj   +1 more source

Fine lines and thin margins: Nutritional and anticoagulation challenges in long-term mechanical circulatory support [PDF]

Hospital Pharmacology
Introduction: Patients receiving long-term mechanical circulatory support (MCS), including Left Ventricular Assist Device (LVAD) and total artificial heart (TAH), represent a high-risk population prone to thromboembolic and bleeding complications. Stable
Stefanović-Nešković Jelena R., Nešković Branimir D., Strugarević Evgenija D.   +2 more
doaj   +1 more source

French‐Speaking Network of Pharmacogenetics (RNPGx) Recommendations for Gene Panel Analysis Through Genotyping or Sequencing in Pharmacogenetics

Fundamental &Clinical Pharmacology, Volume 40, Issue 1, January 2026.
ABSTRACT Background The implementation of pharmacogenetics in clinical practice increasingly relies on multigene panels. Objectives The objective of this study is to develop harmonized recommendations for the design and analytical implementation of multigene pharmacogenetic panels, defining clinically relevant genes and associated regions of interest ...
Nicolas Picard, Estelle Ayme‐Dietrich, Sylvie Quaranta, Tiphaine Adam‐De‐Beaumais, Abd El Kader Ait Tayeb, Hugo Alarcan, Dorra Amor, David Barthelemy, Mouna Ben Sassi, Séverine Cunat, Mouna Daldoul, Hervé Delacour, Marie‐Christine Etienne‐Grimaldi, Xavier Fonrose, Benjamin Hennart, Louis Lebreton, Stephanie Malard, Céline Narjoz, Asma Omezzine, Nicolas Pallet, Léa Payen, Jeanne Petit, Fabienne Thomas, Sameh Trabelsi, Camille Tron, Céline Verstuyft, Paul Vilquin, Jean‐Christophe Boyer, Vincent Haufroid, French‐Speaking Network of Pharmacogenetics (RNPGx)   +29 more
wiley   +1 more source

Functionally Significant Coumarin-Related Variant Alleles and Time to Therapeutic Range in Chilean Cardiovascular Patients

Clinical and Applied Thrombosis/Hemostasis, 2020
Despite the development of new oral agents over the last decade, vitamin K antagonists (VKAs) remain the most widely used anticoagulants for treating and preventing thromboembolism worldwide.
Mario Rojo MSc, Angela Margarita Roco PhD, Marcelo Suarez MSc, Maria Alejandra Lavanderos PhD, Gabriel Verón MSc, Maria Paz Bertoglia PhD, Annabella Arredondo MD, Elena Nieto MD, Juan Carlos Rubilar MSc, Francisca Tamayo PCh, Daniela Cruz MSc, Jessica Muñoz MSc, Gabriela Bravo MSc, Patricio Salas MD, Fanny Mejías MD, Paulo Véliz MSc, Gerald Godoy MSc, Nelson Miguel Varela PhD, G. Llull MSc, Luis Abel Quiñones PhD   +19 more
doaj   +1 more source

Transcatheter Mitral Valve Replacement in Failed Mitral Bioprosthesis: Case Report

Case Reports in Cardiology, Volume 2026, Issue 1, 2026.
Transcatheter valve‐in‐valve mitral valve replacement (ViV TMVR) is an established therapeutic alternative for selected patients with symptomatic degeneration of a surgical mitral bioprosthesis and high or prohibitive surgical risk. We present a 75‐year‐old woman with a failed Pericarbon More 29‐mm mitral bioprosthesis and severe prosthetic mitral ...
Veselin Valkov, Nikolay Dragnev, Josef Bis, Nikolay Kalvachev, Satabdi Datta Choudhury   +4 more
wiley   +1 more source

Genotype-phenotype correlations in patients treated with acenocoumarol / Corelaţii genotip-fenotip la pacienţii trataţi cu acenocumarol

Romanian Journal of Laboratory Medicine, 2014
Scop: Această cercetare are drept scop stabilirea unei corelaţii genotip-fenotip la pacienţii trataţi cu acenocumarol şi studierea factoriilor genetici (polimorfismele VKORC1 şi CYP2C9), care ar putea influenţa valorile INR în timpul iniţierii terapiei ...
Militaru Florentina Claudia, Vesa Ştefan Cristian, Crişan Sorin, Militaru Valentin, Trifa Adrian Pavel, Buzoianu Anca Dana   +5 more
doaj   +1 more source

Optimal anticoagulation strategy for atrial fibrillation ablation: are all direct oral anticoagulants and vitamin K antagonists the same? - a meta-analysis of embolic and bleeding complications in more than 31,500 patients

Romanian Journal of Cardiology
The direct oral anticoagulants (DOACS) such as dabigatran (D), rivaroxaban (R), apixaban (A), and edoxaban (E) have become the leading anticoagulation strategy in atrial fibrillation (AF).
Musat Dan L, Enache Bogdan, Musat Alexandra, Bhatt Advay, Habibi Mohammadali, Kochav Stephanie, Sichrovsky Tina, Preminger Mark W, Mittal Suneet   +8 more
doaj   +1 more source

Bosentan and oral anticoagulants in HIV patients: what we can learn of cases reported so far

Hematology Reports, 2011
Pulmonary arterial hypertension is an infrequent but nevertheless serious life-threatening severe complication of HIV infection. It can be treated with bosentan and oral anticoagulants.
José Antonio Morales-Molina, Juan Enrique Martínez-de la Plata, Olivia Urquízar-Rodríguez, María Angustias Molina-Arrebola   +3 more
doaj   +1 more source