Results 21 to 30 of about 250,937 (292)

Pyrophosphate-Dependent ATP Formation from Acetyl Coenzyme A in Syntrophus aciditrophicus, a New Twist on ATP Formation

open access: yesmBio, 2016
Syntrophus aciditrophicus is a model syntrophic bacterium that degrades key intermediates in anaerobic decomposition, such as benzoate, cyclohexane-1-carboxylate, and certain fatty acids, to acetate when grown with hydrogen-/formate-consuming ...
Kimberly L. James   +17 more
doaj   +1 more source

Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection

open access: yesMolecules, 2017
Coenzyme A (CoA) and acetyl-coenzyme A (acetyl-CoA) play essential roles in cell energy metabolism. Dysregulation of the biosynthesis and functioning of both compounds may contribute to various pathological conditions.
Yevgeniya I. Shurubor   +7 more
doaj   +1 more source

Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae. [PDF]

open access: yesPLoS Genetics, 2017
Eukaryotic cells form stress granules under a variety of stresses, however the signaling pathways regulating their formation remain largely unknown. We have determined that the Saccharomyces cerevisiae lysine acetyltransferase complex NuA4 is required ...
Meaghen Rollins   +7 more
doaj   +1 more source

Acetyl-CoA-Mediated Post-Biosynthetic Modification of Desferrioxamine B Generates N- and NOAcetylated Isomers Controlled by a pH Switch

open access: yes, 2022
Biosynthesis of the hydroxamic acid siderophore desferrioxamine D1 (DFOD1, 6), which is the N-acetylated analogue of desferrioxamine B (DFOB, 5), has been delineated.
Renae M. Ryan (11934270)   +13 more
core   +1 more source

Acetyl-CoA synthetase 2(ACSS2): a review with a focus on metabolism and tumor development

open access: yesDiscover Oncology, 2022
Acetyl-CoA synthetase 2 (ACSS2), an important member of the acetyl-CoA synthetase (ACSS) family, can catalyze the conversion of acetate to acetyl coenzyme A (acetyl-CoA).
Rui Ling   +5 more
doaj   +1 more source

Exploring the Role of ATP-Citrate Lyase in the Immune System

open access: yesFrontiers in Immunology, 2021
Studies over the past decade have revealed that metabolism profoundly influences immune responses. In particular, metabolism causes epigenetic regulation of gene expression, as a growing number of metabolic intermediates are substrates for histone post ...
Monica Dominguez   +5 more
doaj   +1 more source

Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii

open access: yesBMC Biology, 2020
Background Acetyl-CoA is a key molecule in all organisms, implicated in several metabolic pathways as well as in transcriptional regulation and post-translational modification.
Joachim Kloehn   +8 more
doaj   +1 more source

Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program

open access: yesCell Reports, 2023
Summary: Disruption of adipocyte de novo lipogenesis (DNL) by deletion of fatty acid synthase (FASN) in mice induces browning in inguinal white adipose tissue (iWAT). However, adipocyte FASN knockout (KO) increases acetyl-coenzyme A (CoA) and malonyl-CoA
Adilson Guilherme   +18 more
doaj   +1 more source

Regulation of purified rat liver acetyl CoA carboxylase by phosphorylation

open access: yesJournal of Lipid Research, 1983
Acetyl CoA carboxylase was purified from liver of fasted-refed rats to near homogeneity, based on electrophoretic analysis and biotin content. These preparations contained an endogenous protein kinase that catalyzed the transfer of radioactive phosphate ...
J B Allred, G J Harris, J Goodson
doaj   +1 more source

N-acetyltaurine and Acetylcarnitine Production for the Mitochondrial Acetyl-CoA Regulation in Skeletal Muscles during Endurance Exercises

open access: yesMetabolites, 2021
During endurance exercises, a large amount of mitochondrial acetyl-CoA is produced in skeletal muscles from lipids, and the excess acetyl-CoA suppresses the metabolic flux from glycolysis to the TCA cycle. This study evaluated the hypothesis that taurine
Teruo Miyazaki   +7 more
doaj   +1 more source

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