Results 111 to 120 of about 56,989 (293)

The multifaceted roles of ketones in physiology

open access: yesExperimental Physiology, EarlyView.
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili   +3 more
wiley   +1 more source

Mitochondrial fatty acid beta-oxidation

open access: yesEXCLI Journal : Experimental and Clinical Sciences
Peripheral artery disease (PAD) is an atherosclerotic disease impacting over 200 million individuals and the prevalence increases with age. PAD occurs when plaque builds up within the peripheral arteries, leading to reduced blood flow and oxygen supply ...
Cassandra E. Bradley   +7 more
doaj   +1 more source

A simulation study on the role of mitochondria‐sarcoplasmic reticulum Ca2+ interaction in cardiomyocyte energetics during exercise

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend An integrated model of human ventricular myocyte with excitation‐contraction‐energetics coupling was created to systematically analyse the contribution of Ca2+ regulation of mitochondrial enzymes to cardiomyocyte functions during workload transition; i.e. exercise.
Ayako Takeuchi, Satoshi Matsuoka
wiley   +1 more source

Regulation of eukaryotic acetyl-CoA carboxylases

open access: yes, 2018
Many biological carboxylation reactions are catalyzed by ubiquitous biotin-dependent carboxylases. Their mechanism involves three conserved functional components; First, a biotin moiety, covalently linked to the biotin carboxyl carrier protein (BCCP) is carboxylated under ATP consumption at the biotin carboxylase (BC). Then the BCCP translocates to the
openaire   +3 more sources

Fructose catabolism and its metabolic effects: Exploring host–microbiota interactions and the impact of ethnicity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This graphical abstract is a schematic representation highlighting the interactions between dietary fructose, gut microbiota and ethnicity in shaping metabolic health. Abstract Important health disparities are observed in the prevalence of obesity and associated non‐communicable diseases (NCDs), including type 2 diabetes (T2D ...
Florine H.M. Westerbeke   +3 more
wiley   +1 more source

Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation.

open access: yesJournal of Hepatology, 2020
J. Bates   +19 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy