Results 121 to 130 of about 38,176 (241)

Human Milk–Derived Peptide MAMP‐1 Ameliorates Sepsis‐Associated Acute Lung Injury in Mice Through APOA4 and the TLR4/NF‐κB Signaling Pathway

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
The study found that MAMP‐1 can alleviate lung injury by modulating the TLR4 signaling pathway to suppress LPS‐induced inflammation and promote cholesterol reverse transport. ABSTRACT Sepsis‐associated acute lung injury (SALI) significantly jeopardizes the health and survival prospects of neonates.
Shimei Lu   +8 more
wiley   +1 more source

Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis

open access: yesGlia, Volume 74, Issue 3, March 2026.
Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco   +16 more
wiley   +1 more source

RNA‐Based Therapies for Inherited Metabolic Disorders

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri   +5 more
wiley   +1 more source

Understanding the dynamic nature of plant lipid anabolic and catabolic metabolism is key to sustainable oilseed engineering

open access: yesNew Phytologist, Volume 249, Issue 5, Page 2196-2214, March 2026.
Summary Plant‐derived oils are essential sources of reduced carbon and various fatty acid (FA) structures for food, biofuels, and the oleochemical industry. Despite extensive efforts, engineering mainstream oilseed crops to produce high levels of industrially valuable unusual FAs (UFAs) remains challenging.
Prasad Parchuri   +4 more
wiley   +1 more source

A Comprehensive Review of Acne Treatments: Unpacking the Chemical Structures and Effective Bioactive Compounds

open access: yesHealth Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Acne vulgaris is a frequent skin disorder, affecting a large part of the population worldwide, and strongly influencing not only the physical but also the mental aspects of health. The choice of therapy for acne vulgaris is a very difficult one because the multifactorial causality of the disease and interindividual ...
Mobina Tajdari   +5 more
wiley   +1 more source

Bufalin Inhibits Cytokine Storm by Regulating TLR4/TLR3 Signaling Pathway

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Bufalin is one main component of the dried venom from Bufo gargarizans Cantor, which has anti‐tumor, cardiotonic, anti‐inflammatory and other physiological activities. However, in recent years, researchers have mainly paid attention to its anti‐tumor effect and neglected its anti‐inflammatory effect.
Xixi Liu   +11 more
wiley   +1 more source

Human Acetyl-CoA Carboxylase 2 [PDF]

open access: yesJournal of Biological Chemistry, 1997
Lutfi Abu-Elheiga   +3 more
openaire   +1 more source

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