MedComm, Volume 6, Issue 7, July 2025.Schematic graph exhibiting possible mechanism(s) for the role of CK2α and FUNDC1 in high fat diet‐induced hepatic steatosis. Long‐term high fat diet insult dampens FUNDC1‐mediated mitophagy through upregulation of CK2α, prompting disturbed lipid metabolism and lipid accumulation due to compromised mitophagy. Lipotoxicity subsequently promotes lipotoxic
Ke He +11 more
wiley +1 more source
Overexpression of Acetyl CoA Carboxylase 1 and 3 (ACCase1 and ACCase3), and CYP81A21 were related to cyhalofop resistance in a barnyardgrass accession from Arkansas. [PDF]
Plant Signal Behav, 2023 González-Torralva F, Norsworthy JK.
europepmc +1 more source
Plastid-localized acetyl-CoA carboxylase of bread wheat is encoded by a single gene on each of the three ancestral chromosome sets [PDF]
, 1997 Piotr Górnicki +5 more
openalex +1 more source
Phase Separation Regulates Metabolism, Mitochondria, and Diseases
MedComm, Volume 6, Issue 7, July 2025.Mitochondrion‐related liquid–liquid phase separation. (1) Phase separation mediates the self‐assembly of mitochondrial nucleoids (mt‐nucleoids). (2) Phase segregation mediates the formation of mitochondrial RNA granules (MRGs). (3) Phase separation mediates the formation of mitochondrial degradosomes.
Chuan Gao +3 more
wiley +1 more source
The sensor histidine kinase (SLN1) and acetyl-CoA carboxylase (ACC1) coordinately regulate the response of Neurospora crassa to the springtail Sinella curviseta (Collembola: Entomobryidae) attack. [PDF]
Appl Environ Microbiol, 2023 Sun M +7 more
europepmc +1 more source
Elucidation of a promoter activity that directs the expression of acetyl-CoA carboxylase α with an alternative N-terminus in a tissue-restricted fashion [PDF]
, 1998 MICHAEL C. BARBER, Maureen T. Travers
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PROTEOMICS, Volume 25, Issue 13, July 2025.ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo +2 more
wiley +1 more source
Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities. [PDF]
Cell Death Discov, 2023 Fang CT +6 more
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Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase
Pest Management Science, Volume 81, Issue 7, Page 3956-3983, July 2025.The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier +26 more
wiley +1 more source
Acetyl-CoA carboxylase inhibitor increases LDL-apoB production rate in NASH with cirrhosis: prevention by fenofibrate. [PDF]
J Lipid Res, 2023 Dandan M +12 more
europepmc +1 more source