Corrins and the Acetyl-CoA Path of Autotrophic Fixation of Carbon Dioxide in Bacteria
Autotrophic fixation of carbon dioxide in bacteria proceedes not only via the well-known «Calvin cycle», but also via the recently established «acetyl-coenzyme A pathway», meanwhile found to be widely distributed in bacterial anaerobes.
Bernhard Kräutler
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Structure and substrate selectivity of the 750-kDa α6β6 holoenzyme of geranyl-CoA carboxylase. [PDF]
Geranyl-CoA carboxylase (GCC) is essential for the growth of Pseudomonas organisms with geranic acid as the sole carbon source. GCC has the same domain organization and shares strong sequence conservation with the related biotin-dependent carboxylases 3 ...
Huang, Christine S +4 more
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
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Malaria caused by Plasmodium falciparum, remains one of the most fatal parasitic diseases that has affected nearly a third of the world’s population. The major impediment to the treatment of malaria is the emergence of resistance of the P.
Elliasu Y. Salifu +5 more
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Novel Cryptosporidium genotype in wild Australian mice (Mus domesticus) [PDF]
A total of 250 mouse fecal specimens collected from crop farms in Queensland, Australia, were screened for the presence of Cryptosporidium spp. using PCR.
Boxell, A. +4 more
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Determination of acetyl coenzyme A. Interference by a contaminant in malate dehydrogenase
Spectrophotometric determinations of acetyl CoA with malate dehydrogenase and citrate synthase are likely to overestimate the amount of acetyl CoA in solutions containing acetoacetyl CoA, since commercial preparations of malate dehydrogenase may contain ...
I. Mulder
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CoA protects against the deleterious effects of caloric overload in Drosophila [PDF]
We developed a Drosophila model of T2D in which high sugar (HS) feeding leads to insulin resistance. In this model, adipose TG storage is protective against fatty acid toxicity and diabetes.
Baranski, Thomas J +2 more
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The purpose of this study was to investigate the effects of long-chain fatty acids (LCFAs) on AMP-activated protein kinase (AMPK) and acetyl-coenzyme A carboxylase (ACC) phosphorylation and β-oxidation in skeletal muscle.
S. Fediuc, M.P. Gaidhu, R.B. Ceddia
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Carbon assimilation strategies in ultrabasic groundwater: clues from the integrated study of a serpentinization-influenced aquifer [PDF]
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Seyler, L. M., Brazelton, W. J., McLean, C., Putman, L. I., Hyer, A., Kubo, M. D.
Brazelton, William J. +8 more
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