Results 31 to 40 of about 89,329 (265)

A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria [PDF]

open access: yes, 2005
Peer reviewedPublisher ...
Altschul   +48 more
core   +1 more source

Breaking the Cycle, Cholesterol Cycling, and Synapse Damage in Response to Amyloid-ß [PDF]

open access: yes, 2017
Soluble amyloid-β (Aβ) oligomers, a key driver of pathogenesis in Alzheimer disease, bind to cellular prion proteins (PrPC) expressed on synaptosomes resulting in increased cholesterol concentrations, movement of cytoplasmic phospholipase A2 (cPLA2) to ...
Bate, C
core   +3 more sources

Activation of immobilized acetyl-Coenzyme A carboxylase [PDF]

open access: yesBiochemical Journal, 1978
Partially purified acetyl-CoA carboxylase was covalently bound to a Sepharose 4B matrix. Although aggregation was thus prevented, the enzymic activity was stimulated by citrate and isocitrate.
A D, Landman, J, Lampert
openaire   +2 more sources

Biochemical Characterization of Arylamine N-acetyltransferases From Vibrio vulnificus

open access: yesFrontiers in Microbiology, 2021
Vibrio vulnificus is a zoonotic bacterium that is capable of causing highly lethal diseases in humans; this pathogen is responsible for 95% of all seafood-related deaths in the United States. Arylamine N-acetyltransferases (NAT, E.C.
Xinning Liu   +15 more
doaj   +1 more source

Characterization of Genes Involved in the Formation of Aroma Volatiles in "Charentais" Melon Fruit [PDF]

open access: yes, 2004
Volatiles esters impart distinct characteristics to the fruit quality. "Charentais" cantaloupe melon (Cucumis melo "cantalupensis") is characterized by abundant sweetness and aromatic flavour.
El-Sharkawy, Islam   +4 more
core   +1 more source

Metabolic regulation of proteome stability via N-terminal acetylation controls male germline stem cell differentiation and reproduction

open access: yesNature Communications, 2023
The molecular mechanisms connecting cellular metabolism with differentiation remain poorly understood. Here, we find that metabolic signals contribute to stem cell differentiation and germline homeostasis during Drosophila melanogaster spermatogenesis ...
Charlotte M. François   +4 more
doaj   +1 more source

Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]

open access: yes, 2016
AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano   +3 more
core   +2 more sources

The dynamic organization of fungal acetyl-CoA carboxylase [PDF]

open access: yes, 2016
Acetyl-CoA carboxylases (ACCs) catalyse the committed step in fatty-acid biosynthesis: the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. They are important regulatory hubs for metabolic control and relevant drug targets for the treatment of ...
Hagmann, Anna   +4 more
core   +1 more source

Acetyl-coenzyme A [PDF]

open access: yesAutophagy, 2014
As the major lysosomal degradation pathway, autophagy represents the guardian of cellular homeostasis, removing damaged and potentially harmful material and replenishing energy reserves in conditions of starvation. Given its vast physiological importance, autophagy is crucially involved in the process of aging and associated pathologies.
Schroeder, S.   +15 more
openaire   +3 more sources

A multienzyme complex channels substrates and electrons through acetyl-CoA and methane biosynthesis pathways in Methanosarcina.

open access: yesPLoS ONE, 2014
Multienzyme complexes catalyze important metabolic reactions in many organisms, but little is known about the complexes involved in biological methane production (methanogenesis). A crosslinking-mass spectrometry (XL-MS) strategy was employed to identify
Dillon J Lieber   +6 more
doaj   +1 more source

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