Results 61 to 70 of about 113,995,962 (231)
Reduction and Methyl Transfer Kinetics of the Alpha Subunit from Acetyl-Coenzyme A Synthase [PDF]
, 2003 OAK-B135 Stopped-flow was used to evaluate the methylation and reduction kinetics of the isolated alpha subunit of acetyl-Coenzyme A synthase from Moorella thermoacetica.
Lindahl, Paul A. +3 more
core +1 more source
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
Advanced Science, EarlyView.This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
Profiling of cytosolic and peroxisomal acetyl-CoA metabolism in Saccharomyces cerevisiae.
PLoS ONE, 2012 As a key intracellular metabolite, acetyl-coenzyme A (acetyl-CoA) plays a major role in various metabolic pathways that link anabolism and catabolism. In the yeast Saccharomyces cerevisiae, acetyl-CoA involving metabolism is compartmentalized, and may ...
Yun Chen, Verena Siewers, Jens Nielsen
doaj +1 more source
Acetyl-CoA synthetase 2(ACSS2): a review with a focus on metabolism and tumor development
Discover Oncology, 2022 Acetyl-CoA synthetase 2 (ACSS2), an important member of the acetyl-CoA synthetase (ACSS) family, can catalyze the conversion of acetate to acetyl coenzyme A (acetyl-CoA).
Rui Ling +5 more
doaj +1 more source
A capillary electrophoretic assay for acetyl coenzyme A carboxylase
, 2013 A simple off-column capillary electrophoretic (CE) assay for measuring acetyl coenzyme A carboxylase holoenzyme (holo-ACC) activity and inhibition was developed.
Waldrop, Grover L +2 more
core +1 more source
THE PURIFICATION AND PROPERTIES OF ACETYL-COENZYME A CARBOXYLASE KINASE
, 1982 Acetyl-CoA carboxylase kinase has been purified to apparent homogeneity from rat liver. The kinase was found to exist in two forms: bound to carboxylase in a complex or in a free form that is in different stages of aggregation over a wide range of ...
LENT, BRUCE ALAN
core +1 more source
Mitochondrial fatty acid beta-oxidation
EXCLI Journal : Experimental and Clinical SciencesPeripheral artery disease (PAD) is an atherosclerotic disease impacting over 200 million individuals and the prevalence increases with age. PAD occurs when plaque builds up within the peripheral arteries, leading to reduced blood flow and oxygen supply ...
Cassandra E. Bradley +7 more
doaj +1 more source
Creation of Germplasm Resources of Two-line Sterile Rice Resistant to ACCase-inhibiting Herbicides [PDF]
中国水稻科学【Objective】The creation of herbicide-resistant rice germplasm is essential for breeding new herbicide-resistant rice varieties. By using CRISPR/Cas9 gene editing technology, the acetyl-CoA carboxylase OsACC1 gene was edited with the sterile line An 9S as
GUO Jinmeng, TAO Kailiang, ZHU Jun, ZHAO Xueyu, LI Kang, GAN Quan, LIN Cuixiang, WANG Nansheng, YU Hao, SONG Fengshun, LI Juan, SHI Yingyao, NI Dahu
doaj +1 more source
Journal of Experimental & Clinical Cancer ResearchBackground Aberrant glycogen metabolism drives lipid accumulation and adaptive lipid homeostasis reprogramming, a metabolic adaptation critical for sustaining malignant progression and chemoresistance in cholangiocarcinoma (CCA).
Yani Pan +13 more
doaj +1 more source
Neurobiology of Disease, 2012 Brain glucose supplies most of the carbon required for acetyl-coenzyme A (acetyl-CoA) generation (an important step for myelin synthesis) and for neurotransmitter production via further metabolism of acetyl-CoA in the tricarboxylic acid (TCA) cycle ...
Isaac Marin-Valencia +7 more
doaj +1 more source