RNAi-mediated Reduction of a Major Ruminant Specific Milk Allergen Using a Transgenic Mouse Model
, 2012 Milk from dairy cows is an important human food. It contains the protein beta-lactoglobulin (BLG) which is not present in human milk and thought to be a major allergen in the milk of cows. RNA interference (RNAi), mediated by sequence-specific micro RNAs
Jabed, Md Anower
core
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To evaluate the extent to which the appearance of HOD in the brain following systemic administration of a deuterated substrate is due to local brain metabolism versus body metabolism. Methods [6,6‐2H2]glucose, which is transported across the blood‐brain barrier (BBB), and [6,6‐2H2]fructose (Fruc), which does not cross the BBB, were ...
Joseph J. H. Ackerman +5 more
wiley +1 more source
ACETYL COENZYME-A CARBOXYLASE IN SPECIES OF TRITICUM OF DIFFERENT PLOIDY
, 1990 ACETYL COENZYME-A CARBOXYLASE IN SPECIES OF TRITICUM OF DIFFERENT ...
JC HAWKE (17322886), RM LEECH (18713899)
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Role of Carnitine Acetyltransferases in Acetyl Coenzyme A Metabolism in Aspergillus nidulans
, 2011 The flow of carbon metabolites between cellular compartments is an essential feature of fungal metabolism. During growth on ethanol, acetate, or fatty acids, acetyl units must enter the mitochondrion for metabolism via the tricarboxylic acid cycle, and ...
Meryl A. Davis +3 more
core +1 more source
Pediatric Discovery, EarlyView.This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang +6 more
wiley +1 more source
Correlation of acetyl-coenzyme A carboxylase 1 with Th17 and Th1 cells, serving as a potential prognostic biomarker for acute ischemic stroke patients. [PDF]
J Clin Lab Anal, 2022 Jiang J +5 more
europepmc +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
PROTEOMICS, EarlyView.ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Energetics of the Citric Acid Cycle in the Deep Biosphere
Geophysical Monograph Series, Page 303-327., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Peter A. Canovas III, Everett L. Shock
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Acetyl coenzyme A kinetic studies on N-acetylation of environmental carcinogens by human N-acetyltransferase 1 and its NAT1*14B variant. [PDF]
Front Pharmacol, 2022 Habil MR, Doll MA, Hein DW.
europepmc +1 more source
From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies
Portal Hypertension &Cirrhosis, EarlyView.This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu +5 more
wiley +1 more source