Harnessing Photoenzymatic Systems for Intermolecular C–H Fluorination
Despite the remarkable versatility of enzymes for catalyzing complex organic transformations under mild aqueous conditions, no biocatalytic system has been reported for intermolecular C–H fluorination. A radical photoenzymatic approach is introduced that leverages a designed de novo protein scaffold with an unnatural amino acid to achieve precise ...
Yu Zhou +7 more
wiley +2 more sources
Changes of Coenzyme A and Acetyl-Coenzyme A Concentrations in Rats after a Single-Dose Intraperitoneal Injection of Hepatotoxic Thioacetamide Are Not Consistent with Rapid Recovery. [PDF]
Shurubor YI +6 more
europepmc +1 more source
Determination of acetyl coenzyme A in grape berries by high performance liquid chromatography-tandem mass spectrometry [PDF]
Yan Yang, Guangfeng Wu
openalex +1 more source
The article underscores the promising future perspectives of utilizing agro‐industrial waste, envisioning sustainable production processes, and meeting the increasing demand for environmentally friendly and health‐promoting products. ABSTRACT The growing imperative for increased food production has propelled an example alteration in the perception of ...
Fakhar Islam +9 more
wiley +1 more source
Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy. [PDF]
Zhang Y +12 more
europepmc +1 more source
CD38 deficiency influences brain NAD/NAM metabolism. Global CD38 deficiency drives changes in astrocyte mitochondrial, metabolic, senescence, and neurodegenerative‐related genes. CD38 deficiency alters glial reactivity and astrocyte bioenergetics. ABSTRACT CD38 is an ectoenzyme that converts NAD+ to NAM to help maintain bioenergetic homeostasis.
S. Basak +15 more
wiley +1 more source
Substrate specificity of acetyl coenzyme A synthetase.
Smita S. Patel, David R. Walt
openalex +1 more source
A Human Model of Oligodendrocyte Development Shows MCL‐1 Influences Oligodendrocyte Morphogenesis
A unified model of oligodendrocyte differentiation from human embryonic stem cells revealed that MCL‐1 is critical for regulating the expression of oligodendrocyte‐related genes and the morphogenesis of myelinating oligodendrocytes. ABSTRACT Oligodendrocytes are the myelinating cells of the central nervous system.
Melanie Gil +2 more
wiley +1 more source
Assessing Acetyl-Coenzyme A Carboxylase Activity and Inhibition in <i>Caenorhabtidis elegans</i> Using a Partially Purified Protein Extract. [PDF]
Battaglia G +10 more
europepmc +1 more source

