Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]
, 2016 AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano +3 more
core +2 more sources
Draft Genome Sequence for Desulfovibrio africanus Strain PCS. [PDF]
, 2013 Desulfovibrio africanus strain PCS is an anaerobic sulfate-reducing bacterium (SRB) isolated from sediment from Paleta Creek, San Diego, CA. Strain PCS is capable of reducing metals such as Fe(III) and Cr(VI), has a cell cycle, and is predicted to ...
Arkin, Adam P +6 more
core +2 more sources
PanM, an Acetyl-Coenzyme A Sensor Required for Maturation of
mBio, 2012 Coenzyme A (CoA) is essential for cellular chemistry in all forms of life. The pantothenate moiety of CoA is generated from the condensation of pantoate and β-alanine.
Tara N. Stuecker +2 more
doaj +1 more source
Structure and substrate selectivity of the 750-kDa α6β6 holoenzyme of geranyl-CoA carboxylase. [PDF]
, 2015 Geranyl-CoA carboxylase (GCC) is essential for the growth of Pseudomonas organisms with geranic acid as the sole carbon source. GCC has the same domain organization and shares strong sequence conservation with the related biotin-dependent carboxylases 3 ...
Huang, Christine S +4 more
core +2 more sources
Characterization of Genes Involved in the Formation of Aroma Volatiles in "Charentais" Melon Fruit [PDF]
, 2004 Volatiles esters impart distinct characteristics to the fruit quality. "Charentais" cantaloupe melon (Cucumis melo "cantalupensis") is characterized by abundant sweetness and aromatic flavour.
El-Sharkawy, Islam +4 more
core +1 more source
Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]
, 2017 Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio +6 more
core +1 more source
Role of acetylation in nonalcoholic fatty liver disease: a focus on SIRT1 and SIRT3
Exploration of Medicine, 2020 Nonalcoholic fatty liver disease (NAFLD) has become the most prevalent liver chronic disease worldwide. The pathogenesis of NAFLD is complex and involves many metabolic enzymes and multiple pathways.
Fatiha Nassir
doaj +1 more source
Microbial demethylation of dimethylsulfoniopropionate and methylthiopropionate [PDF]
, 2000 As discussed in chapter 1 , there is an increased interest in the production of certain natural sulfur-containing flavor compounds or flavor precursors.
Jansen, Michael,
core +3 more sources
Evolved polygenic herbicide resistance in Lolium rigidum by low-dose herbicide selection within standing genetic variation [PDF]
, 2012 The interaction between environment and genetic traits under selection is the basis of evolution. In this study, we have investigated the genetic basis of herbicide resistance in a highly characterized initially herbicide-susceptible Lolium rigidum ...
Darmency H. +3 more
core +1 more source
Obesity and lipid stress inhibit carnitine acetyltransferase activity[S]
Journal of Lipid Research, 2014 Carnitine acetyltransferase (CrAT) is a mitochondrial matrix enzyme that catalyzes the interconversion of acetyl-CoA and acetylcarnitine. Emerging evidence suggests that this enzyme functions as a positive regulator of total body glucose tolerance and ...
Sarah E. Seiler +9 more
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