Results 121 to 130 of about 2,693 (199)

Proteome and Acetylome Analysis Identifies Novel Pathways and Targets Regulated by Perifosine in Neuroblastoma

, 2017
Perifosine, an Akt inhibitor, has been shown to be effective in controlling neuroblastoma tumor growth. However, studies indicate that in addition to the ability to inhibit Akt, other mechanisms contribute to perifosine’s anti-tumor activity.
Yudi Dong, Carol J. Thiele, Xiao Gu, Wei Tian, Xiaowen Zhang, Zhihui Liu, Yue Zhan, Zhongyan Hua, Zhijie Li   +8 more
core   +1 more source

Image_2_Integrative Proteome and Acetylome Analyses of Murine Responses to Cryptococcus neoformans Infection.TIF

, 2020
Cryptococcus neoformans is a causative agent for pulmonary infection and meningoencephalitis. Understanding the host’s response to C. neoformans infection is critical for developing effective treatment.
Zhijie Zhang (227551), Wei Du (88790), Hailong Li (216327), Dancheng Li (7022363), Tianshu Sun (7022348), Yanjian Li (7022345), Chen Ding (123510)   +6 more
core   +1 more source

Comprehensive Proteome and Acetylome Analysis of Needle Senescence in Larix gmelinii

International Journal of Molecular Sciences
Leaf senescence is essential for the growth and development of deciduous trees in the next season. Larix gmelinii, a deciduous coniferous tree, exhibits its most distinctive feature by turning yellow in the autumn and eventually shedding its leaves, resulting in significant changes in its appearance during the fall.
Xuting Zhang, Jinyuan Shan, Jiaxiu Wang, Yanxia Zhang, Feiyun Yang, Bin Liu, Lifeng Zhang, Guojing Li, Ruigang Wang   +8 more
openaire   +2 more sources

KAT2-mediated PLK4 acetylation contributes to genomic stability by preserving centrosome number

Molecular & Cellular Oncology, 2017
We have recently identified the first human lysine (K) acetyltransferase 2A and 2B (called KAT2A/2B; known also as GCN5/PCAF, respectively)-dependent acetylome and revealed a mechanism by which KAT2A/2B-mediated acetylation of serine/threonine polo-like ...
Marjorie Fournier, László Tora
doaj   +1 more source

Deep, quantitative coverage of the lysine acetylome using novel anti-acetyl-lysine antibodies and an optimized proteomic workflow

, 2015
Introduction of antibodies specific for acetylated lysine has significantly improved the detection of endogenous acetylation sites by mass spectrometry.
Svinkina, T., Silva, J.C., Udeshi, N.D., Gu, H., Kuhn, E., Mertins, P., Qiao, J., Jaffe, J.D., Carr, S.A., Fereshetian, S.   +9 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

LAFEM: A Scoring Model to Evaluate Functional Landscape of Lysine Acetylome

Molecular & Cellular Proteomics
Protein lysine acetylation is a critical post-translational modification involved in a wide range of biological processes. To date, about 20,000 acetylation sites of Homo sapiens were identified through mass spectrometry-based proteomic technology, but more than 95% of them have unclear functional annotations because of the lack of existing ...
Liang, Jun-Ze, Li, De-Hua, Xiao, Yong-Chun, Shi, Fu-Jin, Zhong, Tairan, Liao, Qian-Ying, Wang, Yang, He, Qing-Yu   +7 more
openaire   +2 more sources

Corrigendum: Proteome and Acetyl-Proteome Profiling of Camellia sinensis cv. ‘Anji Baicha’ during Periodic Albinism Reveals Alterations in Photosynthetic and Secondary Metabolite Biosynthetic Pathways

Frontiers in Plant Science, 2018
Yan-Xia Xu, Wei Chen, Chun-Lei Ma, Si-Yan Shen, Yan-Yan Zhou, Lian-Qi Zhou, Liang Chen   +6 more
doaj   +1 more source

StSIRT1 regulates potato dormancy through deacetylation of peroxidase-like 3 at K37. [PDF]

Sci Adv
Hu Q, Dong Y, Hu H, Xiang Y, Liu B, Wong TW, Ban Z, Luo Z, Li L.   +8 more
europepmc   +1 more source

Histone Acetylation Dynamics Regulate Fungal Development, Pathogenicity, and Mycotoxin Biosynthesis. [PDF]

J Fungi (Basel)
Gong C, Li Z, Xu D, Sun D, Wang Z, Du X, Zhang Y, Qi X.   +7 more
europepmc   +1 more source