Results 101 to 110 of about 2,693 (199)

Additional file 6 of H3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts

open access: yes, 2020
Additional file 6. Supplementary Figure 6. Sex-specific H3K27ac acetylome and transcriptome profiles between male and female patients with concentric remodeling.
Krebber, Merle M.   +41 more
core   +1 more source

A comprehensive analysis of the lysine acetylome reveals diverse functions of acetylated proteins during de -etiolation in Zea mays

open access: yes, 2020
Lysine acetylation is one of the most important post-translational modifications and is involved in multiple cellular processes in plants. There is evidence that acetylation may play an important role in light-induced deetiolation, a key developmental ...
Chao, Qing   +6 more
core   +1 more source

Table_4_Comprehensive Proteome and Lysine Acetylome Analysis Reveals the Widespread Involvement of Acetylation in Cold Resistance of Pepper (Capsicum annuum L.).XLSX

open access: yes, 2021
Pepper is a typical warmth-loving vegetable that lacks a cold acclimation mechanism and is sensitive to cold stress. Lysine acetylation plays an important role in diverse cellular processes, but limited knowledge is available regarding acetylation ...
Xuexiao Zou (6273404)   +10 more
core   +1 more source

Quantitative analysis of the lysine acetylome reveals the role of SIRT3-mediated HSP60 deacetylation in suppressing intracellular Mycobacterium tuberculosis survival

open access: yesMicrobiology Spectrum
Protein acetylation and deacetylation are key epigenetic modifications that regulate the initiation and development of several diseases. In the context of infection with Mycobacterium tuberculosis (M.
Chuanzhi Zhu   +11 more
doaj   +1 more source

Uncoupling the Mitogenic and Metabolic Functions of FGF1 by Tuning FGF1-FGF Receptor Dimer Stability

open access: yesCell Reports, 2017
Lysine acetylation is involved in various biological processes and is considered a key reversible post-translational modification in the regulation of gene expression, enzyme activity, and subcellular localization. This post-translational modification is
Zhifeng Huang   +14 more
doaj   +1 more source

KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification

open access: yesNature Communications, 2016
The acetyltransferases KAT2A and KAT2B are essential regulators of transcription, cell cycle progression and DNA repair. Here the authors describe a KAT2A/2B-dependent acetylome, and show that acetylation of the protein kinase PLK4 contributes to the ...
Marjorie Fournier   +11 more
doaj   +1 more source

Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome

open access: yes, 2018
The acetyltransferases CBP and p300 are multifunctional transcriptional co-activators. Here, we combined quantitative proteomics with CBP/p300-specific catalytic inhibitors, bromodomain inhibitor, and gene knockout to reveal a comprehensive map of ...
Satpathy, Shankha   +31 more
core   +1 more source

Data_Sheet_1_A Comprehensive Analysis of the Lysine Acetylome in the Aquatic Animals Pathogenic Bacterium Vibrio mimicus.docx

open access: yes, 2022
Protein lysine acetylation is an evolutionarily conserved post-translational modification (PTM), which is dynamic and reversible, playing a crucial regulatory role in almost every aspect of metabolism, of both eukaryotes and prokaryotes.
Fuyuan Zeng (10101388)   +8 more
core   +1 more source

Table_4_A comprehensive mouse brain acetylome-the cellular-specific distribution of acetylated brain proteins.xlsx

open access: yes, 2022
Nε-lysine acetylation is a reversible posttranslational modification (PTM) involved in multiple physiological functions. Genetic and animal studies have documented the critical roles of protein acetylation in brain development, functions, and various ...
Yuting Ye (419736)   +9 more
core   +1 more source

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