Results 81 to 90 of about 2,693 (199)

Genome-Wide Analyses of Proteome and Acetylome in Zymomonas mobilis Under N2-Fixing Condition

Frontiers in Microbiology, 2021
Zymomonas mobilis, a promising candidate for industrial biofuel production, is capable of nitrogen fixation naturally without hindering ethanol production. However, little is known about the regulation of nitrogen fixation in Z. mobilis.
Ayesha Nisar, Ayesha Nisar, Xiangxu Gongye, Yuhuan Huang, Yuhuan Huang, Sawar Khan, Mao Chen, Mao Chen, Bo Wu, Mingxiong He   +9 more
doaj   +1 more source

Safe and Stable Germline Transmission of MSTN Mutations in Cattle

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT With the global population expected to reach 10 billion by 2050, sustainable livestock production is critical. Gene editing of the myostatin (MSTN) gene represents a promising strategy to enhance muscle growth in cattle. In this study, MSTN‐mutated founder (F0) cows were used to generate F1 offspring via ovum pick‐up, in vitro fertilization ...
Gyeong‐Min Gim, Bae Young Choi, Jeongbin Yi, Kyeong‐Hyeon Eom, Soo‐Young Yum, Dae‐Jin Jung, Do‐Yoon Kim, Bokyoung Yang, Jong‐Seo Kim, Donghwan Shim, Goo Jang   +10 more
wiley   +1 more source

Understanding the acetylome: translating targeted proteomics into meaningful physiology

American Journal of Physiology-Cell Physiology, 2014
It is well established that exercise elicits a finely tuned adaptive response in skeletal muscle, with contraction frequency, duration, and recovery shaping skeletal muscle plasticity. Given the power of physical activity to regulate metabolic health, numerous research groups have focused on the molecular mechanisms that sense, interpret, and ...
Philp, Andrew, Rowland, Thomas, Perez-Schindler, Joaquin, Schenk, Simon   +3 more
openaire   +3 more sources

Table_1_Genome-Wide Analyses of Proteome and Acetylome in Zymomonas mobilis Under N2-Fixing Condition.XLSX

, 2021
Zymomonas mobilis, a promising candidate for industrial biofuel production, is capable of nitrogen fixation naturally without hindering ethanol production. However, little is known about the regulation of nitrogen fixation in Z. mobilis.
Sawar Khan (6324086), Yuhuan Huang (11532565), Mingxiong He (653738), Bo Wu (16141), Ayesha Nisar (6324083), Mao Chen (92698), Xiangxu Gongye (11532562)   +6 more
core   +1 more source

Lactate metabolism and protein lactylation in programmed cell death: From novel mechanism to therapeutic strategies in human diseases

Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.
This review highlights protein lactylation as a metabolic‐epigenetic regulator linking lactate reprogramming to programmed cell death. By modulating histone and non‐histone targets, lactylation reshapes cell fate decisions and represents a promising biomarker and therapeutic target in human diseases.
Yue Chen, Xiwen Wang, Xiuping Wang, Na Lin, Wenjie Wang, Ruiqi Fu, Yutong Wu, Yi Liu, Hengwei Liu   +8 more
wiley   +1 more source

Proteome and Acetyl-Proteome Profiling of Camellia sinensis cv. ‘Anji Baicha’ during Periodic Albinism Reveals Alterations in Photosynthetic and Secondary Metabolite Biosynthetic Pathways

Frontiers in Plant Science, 2017
Tea leaf color is not only important from an aesthetics standpoint but is also related to tea quality. To investigate the molecular mechanisms that determine tea leaf color, we examined Camellia sinensis cv.
Yan-Xia Xu, Wei Chen, Chun-Lei Ma, Si-Yan Shen, Yan-Yan Zhou, Lian-Qi Zhou, Liang Chen   +6 more
doaj   +1 more source

Towards the N-Terminal Acetylome: An N-Terminal Acetylated Peptide Enrichment Method Using CNBr-Activated Sepharose Resin

, 2012
Protein N-terminal acetylation (Nα-acetylation) is observed widely from prokaryotes to eukaryotes. It gains increased importance in biological field, due to its multiple roles in many aspects of the protein life, such as assembly, stability, activity ...
Zhang, Xumin, Højrup, Peter; id_orcid, Xumin Zhang, Peter Højrup   +3 more
core   +1 more source

Discovery of Post‐Translationally Modified Epitopes in Autoimmunity: Someone Has to Fish so Everyone Can Eat

Immunological Reviews, Volume 343, Issue 1, October 2026.
ABSTRACT Post‐translational modifications (PTMs) chemically diversify the ~20,000 genomically encoded proteins into millions of functional variants, and this diversity has profound consequences for T cell‐mediated immune responses. PTM‐reactive T cells have been identified across numerous autoimmune diseases and, in several cases, implicated directly ...
Sanya Arshad, Benjamin M. Cameron, Alok V. Joglekar   +2 more
wiley   +1 more source

Histone acetylome-wide association study of tuberculosis [PDF]

, 2019
Abstract Host-cell chromatin changes are thought to play an important role in the pathogenesis of infectious diseases. Here, we describe the first histone acetylome-wide association study (HAWAS) of an infectious disease, based on genome-wide H3K27 acetylation profiling of peripheral granulocytes and monocytes from ...
del Rosario, Ricardo C.H., Poschmann, Jeremie, Kumar, Pavanish, Cheng, Catherine Y., Ong, Seow Theng, Hajan, Hajira Shreen, Kumar, Dilip, Marzuki, Mardiana, Lu, Xiaohua, Lee, Andrea, Tang, Yanxia, Chee, Cynthia Bin Eng, Lim, Carey, Lee, Bernett, Lum, Josephine, Zolezzi, Francesca, Poidinger, Michael, Rotzschke, Olaf, Khor, Chiea Chuen, Wang, Yee T., Chandy, K. George, De Libero, Gennaro, Singhal, Amit, Prabhakar, Shyam   +23 more
openaire   +1 more source

The Role of SIRT1 in Mediating Bone Marrow Edema and Its Interface With Bone Remodeling

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
ABSTRACT Background Bone marrow edema (BME), a common magnetic resonance imaging (MRI) finding characterized by increased fluid signal, is associated with pain and structural deterioration in conditions such as osteoarthritis and avascular necrosis. The pathophysiology of BME involves a complex interplay of vascular leakage, inflammation, microdamage ...
Yiming Chen, Xinyue Li, Zhongji Zheng, Zhihong Liu, Tao Xu, Yuanyi Tang   +5 more
wiley   +1 more source