Results 31 to 40 of about 3,011 (167)
eLife, 2020 Acid-sensing ion channels (ASICs) are proton-gated members of the epithelial sodium channel/degenerin (ENaC/DEG) superfamily of ion channels and are expressed throughout the central and peripheral nervous systems.
Nate Yoder, Eric Gouaux
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Acid-sensing (proton-gated) ion channels (ASICs) in GtoPdb v.2021.3
IUPHAR/BPS Guide to Pharmacology CITE, 2021 Acid-sensing ion channels (ASICs, nomenclature as agreed by NC-IUPHAR [45, 2, 3]) are members of a Na+ channel superfamily that includes the epithelial Na+ channel (ENaC), the FMRF-amide activated channel (FaNaC) of invertebrates, the degenerins (DEG) of Caenorhabitis elegans, channels in Drosophila melanogaster and 'orphan' channels that include ...
Lachlan D. Rash, Stephan Kellenberger
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Acid Sensing Ion Channels (ASICs) in NS20Y cells – potential role in neuronal differentiation [PDF]
Molecular Brain, 2016 Cultured neuronal cell lines can express properties of mature neurons if properly differentiated. Although the precise mechanisms underlying neuronal differentiation are not fully understood, the expression and activation of ion channels, particularly those of Ca(2+)-permeable channels, have been suggested to play a role. In this study, we explored the
Zaven O’Bryant +5 more
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Biomolecules, 2019 Acid-sensing ion channel (ASIC) channels belong to the family of ligand-gated ion channels known as acid-sensing (proton-gated) ion channels. Only a few activators of ASICs are known.
Dmitry I. Osmakov +4 more
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A COMPUTATIONAL STUDY ON Ca²⁺ MODULATION OF ASIC 1 PHARMACOLOGIC PROPERTIES
Studia Universitatis Babes-Bolyai Chemia, 2021 Acid-sensing ion channel (ASIC) is involved in important processes like synaptic plasticity and learning, fear and anxiety, pain sensation. Due to its role in neurodegeneration and neuroinflammation, the channel is a viable pharmacological target.
Raluca NICULAE +3 more
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Physiological Reports, 2023 Peripheral artery diseases (PAD) increases muscle afferent nerve‐activated reflex sympathetic nervous and blood pressure responses during exercise (termed as exercise pressor reflex).
Qin Li, Lu Qin, Jianhua Li
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Modulation of Ionotropic Glutamate Receptors and Acid-Sensing Ion Channels by Nitric Oxide
Frontiers in Physiology, 2012 Ionotropic glutamate receptors (iGluR) are ligand-gated ion channels and are densely expressed in broad areas of mammalian brains. Like iGluRs, acid-sensing ion channels (ASIC) are ligand (H+)-gated channels and are enriched in brain cells and ...
John Q Wang +7 more
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Frontiers in Physiology, 2021 Acid-Sensing Ion Channels (ASICs) are proton-gated sodium-selective cation channels that have emerged as metabolic and pain sensors in peripheral sensory neurons and contribute to neurotransmission in the CNS.
Daniel S. Matasic +18 more
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Acid-Sensing Ion Channel 2: Function and Modulation
Membranes, 2022 Acid-sensing ion channels (ASICs) have an important influence on human physiology and pathology. They are members of the degenerin/epithelial sodium channel family.
Andy Sivils +3 more
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Acid-sensing (proton-gated) ion channels (ASICs) in GtoPdb v.2023.1
IUPHAR/BPS Guide to Pharmacology CITE, 2023 Acid-sensing ion channels (ASICs, nomenclature as agreed by NC-IUPHAR [48, 2, 3]) are members of a Na+ channel superfamily that includes the epithelial Na+ channel (ENaC), the FMRF-amide activated channel (FaNaC) of invertebrates, the degenerins (DEG) of Caenorhabitis elegans, channels in Drosophila melanogaster and 'orphan' channels that include ...
Lachlan D. Rash, Stephan Kellenberger
openaire +3 more sources