Results 81 to 90 of about 104,808 (264)

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Ketone Body Metabolism in Ascorbic Acid Deficiency

, 1956
The in vitro formation of ketone bodies by liver tissues of ascorbic acid-deficient, and control (pair-fed) guinea pigs was studied. The data revealed that the spontaneous production of ketone bodies by the liver of the ascorbic acid-deficient guinea ...
Albert F. Debons, Habeeb Bacchus, John W. Wallace   +2 more
core   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

The variation of the ascorbic acid content from potato tubers during storage, under house cellar conditions

, 2008
This work pointed out the change of the ascorbic acid (vitamin C) content from potato tubers, stored for three months under apartment house cellar conditions.
Fărtăiș, Liviu-Mihai, Herghelegiu, Ioana, Avramiuc, Marcel   +2 more
core  

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Candidate Genes and Quantitative Trait Loci Affecting Fruit Ascorbic Acid Content in Three Tomato Populations

, 2007
International audienceFresh fruit and vegetables are a major source of ascorbic acid ( vitamin C), an important antioxidant for the human diet and also for plants. Ascorbic acid content in fruit exhibits a quantitative inheritance.
Garchery, Cécile, Stevens, Rebecca, Buret, Michel, Causse, Mathilde, Rothan, Christophe, Baldet, Pierre, Duffé, Philippe   +6 more
core   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

ASCORBIC ACID AND ACCLIMATIZATION TO COLD ENVIRONMENT

, 1947
A large increase in the ascorbic acid content has been shown to occur in the tissues of the white rat (able to synthesize that vitamin) after prolonged exposure and adaptation to cold (+ 4° to − 4 °C.).
Louis-Paul Dugal, Mercedes Thérien
core   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Applications of permanganate chemiluminescence to the analysis of food components

Chemiluminescent oxidations with manganese reagents have been investigated using flow and spectroscopic techniques. An assay has been developed for ascorbic acid using the chemiluminescent oxidation of ascorbic acid with permanganate in acid ...
Agater, Irena Barbara
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