Laryngeal cancer is diagnosed approximately 20% of head and neck cancers worldwide1. Among the potential sphingolipid-based treatment methods for the treatment of these fatal cancers2 acid ceramidase inhibition is indicated as a beneficial treatment ...
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Role of Acid Ceramidase In Xenografted Zebrafish Glioblastoma Model.
Glioblastoma is considered as the most aggressive form of brain tumor with overall survival less than fifteen months after diagnosis, even with multimodal therapy.
Martinez Ramirez, Hilda
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Upregulation of acid ceramidase contributes to tumor progression in tuberous sclerosis complex. [PDF]
Astrinidis A +23 more
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Inhibitory effect of Porphyromonas gingivalis-derived phosphoethanolamine dihydroceramide on acid ceramidase expression in oral squamous cells. [PDF]
Yamada C +7 more
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Spinal muscular atrophy-like phenotype in a mouse model of acid ceramidase deficiency. [PDF]
Nagree MS +13 more
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Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia. [PDF]
Ung J +14 more
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Acid ceramidase involved in pathogenic cascade leading to accumulation of α-synuclein in iPSC model of GBA1-associated Parkinson's disease. [PDF]
Kumar M +5 more
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Interfacial Regulation of Acid Ceramidase Activity [PDF]
Thomas Linke +6 more
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Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis. [PDF]
Xiao J, Zeng W, Zhang P, Zhou Y, Fang Q.
europepmc +1 more source
Fluorogenic Tissue-Based Assessment of Acid Ceramidase Activity. [PDF]
Manabat A +4 more
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