Results 141 to 150 of about 3,455 (202)

Deficient GATA6-ACKR3/CXCR7 signaling leads to bicuspid aortic valve

AbstractThe cardiac outflow tract (OFT) transiently links the ventricles to the aortic sac and gives rise to the arterial valves. Abnormalities of the arterial valves, mainly bicuspid aortic valve (BAV), are the commonest congenital anomalies.Gata6inactivating mutations cause cardiac OFT defects and BAV, but the cellular and molecular mechanisms are ...
José Luis de la Pompa, Rebeca Piñeiro-Sabarís, Donal MacGrogan   +2 more
openaire   +1 more source

Inhibition of constitutive activity of the atypical chemokine receptor 3 by the small-molecule inverse agonist VUF16840. [PDF]

Mol Pharmacol
Bosma R, Nesheva D, Rijnsburger M, Riemens R, Adamska JM, Meyrath M, Mobach S, Buzink CM, van der Pol S, de Esch IJP, Szpakowska M, Wijtmans M, Chevigne A, Vischer HF, Leurs R.   +14 more
europepmc   +1 more source

Osr1 orchestrates posterior second heart field cell migration for outflow tract formation. [PDF]

Commun Biol
Liu L, Li J, Cheng H, Xiang M, Liu J, Kidd B, Li J, Qin Y, Peng H, Ji JY, Kelly RG, Jiang R, Zhang K, Xie L.   +13 more
europepmc   +1 more source

Hsa-miR-100-5p promotes the development and progression of gastric cancer through targeted atypical chemokine receptor 3. [PDF]

Int J Clin Exp Pathol
Wang XL, Jiang JC, Song JY, Ni JY, Song L, Xiao JZ, Fu D, Chen ZY, Cao YF.   +8 more
europepmc   +1 more source

Atypical regulation of an atypical chemokine receptor: ACKR3 'senses' CXCR4 activation through phosphorylation.

Biophysical Journal, 2023
Christopher T. Schafer, Qiuyan Chen, J. Tesmer, T. Handel   +3 more
semanticscholar   +1 more source

Constructing a chemokine-based model and identifying <i>CCL17</i> as a core biomarker associated with immune infiltrates in thyroid cancer. [PDF]

Transl Cancer Res
Zhang M, Zou B, Li Q, Zhao Y, He Y.
europepmc   +1 more source

Chemokine-receptor-guided B-cell immunity in cardiovascular disease. [PDF]

Basic Res Cardiol
Yerly A, van der Vorst EPC, Schindewolf M, Kotelis D, Noels H, Döring Y.   +5 more
europepmc   +1 more source

Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor. [PDF]

Nature
Chen Q, Schafer CT, Mukherjee S, Wang K, Gustavsson M, Fuller JR, Tepper K, Lamme TD, Aydin Y, Agrawal P, Terashi G, Yao XQ, Kihara D, Kossiakoff AA, Handel TM, Tesmer JJG.   +15 more
europepmc   +1 more source

Distinct membrane binding properties of the two non-visual arrestins. [PDF]

Commun Biol
Killeen TD, Tepper K, Miller KW, Aydin Y, Zhuo Y, Zhao S, Conley JM, Tat R, Klug CS, Marchese A, Raicu V, Chen Q.   +11 more
europepmc   +1 more source

GPR15LG binds CXCR4 and synergistically modulates CXCL12-induced cell signaling and migration. [PDF]

Cell Commun Signal
Albers DPJ, Novikova S, Vieyto-Nuñez J, Almeida-Hernández Y, Pastorio C, Klassen F, Weiss D, von Maltitz P, Jaikishan J, Datta M, Jumaa H, Jebaraj BMC, Stilgenbauer S, Kumar M, Maity PC, Buske C, Stifel U, Zinngrebe J, Fischer-Posovszky P, Chevigné A, Kirchhoff F, Sanchez-Garcia E, Münch J, Harms M.   +23 more
europepmc   +1 more source