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Total alkaloids of Aconitum carmichaelii Debx alleviate cisplatin-induced acute renal injury by inhibiting inflammation and oxidative stress related to gut microbiota metabolism.

Phytomedicine
BACKGROUND Cisplatin-induced acute kidney injury (AKI) is a complex and serious clinical issue, representing a major cause of hospital-acquired AKI.
Xi Yang   +7 more
semanticscholar   +1 more source

Aromatic acid derivatives from the lateral roots of Aconitum carmichaelii

Journal of Asian Natural Products Research, 2014
Seven new aromatic acid derivatives (1-7), together with five known analogs, were isolated from the lateral roots of Aconitum carmichaelii. Structures of the new compounds were determined by spectroscopic and chemical methods as 4-methyl ( - )-(R)-hydroxyeucomate (1), 4-butyl ( - )-(R)-hydroxyeucomate (2), 4-butyl-1-methyl (+)-(R)-2-O-(4'-hydroxy-3 ...
Zhi-Bo, Jiang   +7 more
openaire   +2 more sources

Transcriptome Analysis of Aconitum carmichaelii Identifies Genes Involved in Terpenoid, Alkaloid and Phenylpropanoid Biosynthesis

International Journal of Agriculture and Biology
In this study, RNA sequencing of six A. carmichaelii organs was performed using the Illumina HiSeq 2500 high-throughput platform. The de novo assembly yielded 103,338 unigenes, a total of 19,807 unigenes were annotated and 12,061 were assigned to 129 ...
Jihai Gao   +6 more
semanticscholar   +1 more source

Two new pyrazines from the parent roots of Aconitum carmichaelii

Biochemical Systematics and Ecology, 2013
Two new pyrazines, aconicarpyrazine A (1) and aconicarpyrazine B (2), together with five known heterocyclic compounds: adenosine (3), uridine (4), hypoxanthine (5), nicotinamide (6), and uracil (7), were isolated from the parent roots of Aconitum carmichaelii. The structures of these alkaloids were elucidated by spectroscopic analysis, including 2D NMR
Li Guo   +7 more
openaire   +1 more source

Identification and quality evaluation of different processed products of Aconitum carmichaelii by ultra-high-performance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry and ultra-high-performance liquid chromatography-tandem mass spectrometry.

Journal of Separation Science, 2023
Aconitum carmichaelii is widely used to treat chronic and intractable diseases due to its remarkable curative effect, but it is also a highly toxic herb with severe cardiac and neurotoxicity.
Nina Wei   +8 more
semanticscholar   +1 more source

An overview of the research progress on Aconitum carmichaelii Debx.:active compounds, pharmacology, toxicity, detoxification, and applications.

Journal of Ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE Aconitum carmichaelii Debx. is the most widely distributed species of Aconitum plants in China and has a long history of medicinal use. Because of its toxicity, A.
Xv Liang   +6 more
semanticscholar   +1 more source

Genetic diversity, plant growth promotion potential and antimicrobial activity of culturable endophytic actinobacteria isolated from Aconitum carmichaelii Debeaux.

Journal of Applied Microbiology, 2023
AIM This study evaluated phylogenetic diversity, plant growth promotion capacity, antifungal activity and biocontrol potential of culturable actinobacterial endophytes isolated from medicinal plant Aconitum carmichaelii Debeaux.
Lan Zou   +5 more
semanticscholar   +1 more source

Two new dianthramide glucosides with cardiomyocytes protective activity from Aconitum carmichaelii

Phytochemistry Letters, 2013
Abstract Two new dianthramide glucosides, N-(2′-β- d -glucopyranosyl-5′-hydroxysalicyl)-4-hydroxy-3-methoxyanthranilic acid methyl ester (1) and N-(2′-β- d -glucopyranosyl-5′-hydroxysalicyl)-4-hydroxyanthranilic acid methyl ester (2), together with five known glycosides, were isolated from the lateral roots of Aconitum carmichaelii.
Cheng-Jun He   +8 more
openaire   +1 more source

First Report of Root Rot Caused by Ilyonectria robusta in the Medicinal Herb Aconitum carmichaelii in China.

Plant Disease, 2023
Aconitum carmichaelii Debeaux is used as a traditional Chinese medicine with antiarrhythmic, antiinflammatory and other pharmacological functions. It is widely cultivated in China. According to our survey, about 60% of A.
Hongsu Wang   +11 more
semanticscholar   +1 more source

Two 2-(quinonylcarboxamino)benzoates from the lateral roots of Aconitum carmichaelii

Chinese Chemical Letters, 2015
Abstract Two new 2-(quinonylcarboxamino)benzoates, named aconicarmiquinamides A (1) and B (2), were isolated from an aqueous extract of the lateral roots of Aconitum carmichaelii. Their structures were determined by spectroscopic data analysis, and confirmed by comparison with synthetic methyl 3,6-bis(diethylamino)benzoqunonylcarboxylate (3).
Zhi-Bo Jiang   +7 more
openaire   +1 more source

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