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Unlocking the hidden potential: Enhancing the utilization of stems and leaves through metabolite analysis and toxicity assessment of various parts of Aconitum carmichaelii.

Journal of Ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE Aconitum carmichaelii is widely used in traditional Chinese medicine clinics as a bulk medicinal material. It has been used in China for more than two thousand years.
Yinlin Zhou   +8 more
semanticscholar   +1 more source

Safety evaluations of the processed lateral root of Aconitum carmichaelii Debx. And its hepatotoxicity mechanisms in rats.

Journal of Ethnopharmacology, 2022
ETHNOPHARMACOLOGICAL RELEVANCE The processed lateral root of Aconitum carmichaelii Debx. is known as Fuzi, an extensively used Traditional Chinese Medicine to treat cardiovascular diseases, rheumatism arthritis, bronchitis, pains, and hypothyroidism, etc.
Xiaoyu Ji   +5 more
semanticscholar   +1 more source

First Report of Pectobacterium versatile Causing Soft Rot in Aconitum carmichaelii Debeaux in China

Plant Disease
Aconitum carmichaelii Debeaux is a perennial herbaceous plant within the Ranunculaceae family. The processed lateral roots of A. carmichaelii, known as "Fuzi", are widely used as traditional Chinese medicinal materials for the treatment of various human ...
Hongji Hou   +8 more
semanticscholar   +1 more source

New antidepressant diterpenoid alkaloids from Aconitum carmichaelii Debeaux: Potential inhibitors of NLRP3 activation.

Bioorganic chemistry (Print)
Targeting NOD-like receptor protein 3 (NLRP3) holds promise as a novel strategy for treating depression. Chemical investigation of the lateral roots of Aconitum carmichaelii Debeaux (Fuzi) led to the isolation of five new diterpenoid alkaloids ...
Wei-Feng Yin   +8 more
semanticscholar   +1 more source

The expression of AcIDI1 reveals diterpenoid Alkaloids' allocation strategies in the roots of Aconitum carmichaelii Debx.

Gene
Isopentenyl diphosphate isomerase (IDI), a key enzyme in the biosynthetic pathway of diterpenoid alkaloids (DAs), plays an essential regulatory role in the synthesis and accumulation of DAs. In this study, the coding sequence (CDS) of AcIDI1 was isolated
Yiwen Hu   +3 more
semanticscholar   +1 more source

New C 19 -diterpenoid alkaloids from the parent roots of Aconitum carmichaelii

Tetrahedron Letters, 2017
Abstract Aconitum carmichaelii is a widely used traditional Chinese medicine and important source of clinical drugs. The parent roots of A. carmichaelii were investigated resulting in the isolation and identification of five new C 19 - diterpenoid alkaloids; 14 α -benzoyloxy- N -ethyl-15 α -hydroxy-1 α ,6 α ,8 β ,16 β ,18-pentamethoxyaconitane ...
Xing-Xing Zong   +6 more
openaire   +1 more source

Investigation of the drug-drug interaction and incompatibility mechanism between Aconitum carmichaelii Debx and Pinellia ternata (Thunb.) Breit.

Journal of Ethnopharmacology
ETHNOPHARMACOLOGICAL RELEVANCE The combination of Aconitum carmichaelii Debx (Chuanwu, CW) and Pinellia ternata (Thunb.) Breit (Banxia, BX) forms an herbal pair within the eighteen incompatible medicaments (EIM), indicating that BX and CW are ...
Minglei Ge   +10 more
semanticscholar   +1 more source

Qualitative and quantitative analysis of aconitine-type and lipo-alkaloids of Aconitum carmichaelii roots

Journal of Chromatography A, 2009
By optimizing the extraction and analytical conditions, a reliable and precise HPLC method coupled with photodiode array detection (HPLC-DAD) has been developed for the identification and quantification of three major aconitine-type alkaloids (aconitine, mesaconitine, hypaconitine) in the roots of Aconitum carmichaelii Debeaux. The qualitative analysis
Csupor Dezső   +5 more
openaire   +3 more sources

Two unique C21-diterpenoid alkaloids from Aconitum carmichaelii

Chinese Chemical Letters, 2022
Jingfang Zhang   +6 more
openaire   +1 more source

A novel Agroathelia species causing southern blight on Aconitum carmichaelii in Sichuan, China

Plant Pathology
Aconitum carmichaelii is a prominent medicinal plant widely used in Asian countries. Southern blight is one of the main soilborne diseases and has severely restricted the sustainable development of A. carmichaelii.
Siyu Wang   +8 more
semanticscholar   +1 more source

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