Antisense phosphorodiamidate morpholino oligomers retain activity in Burkholderia cepacia complex biofilm [PDF]
Frontiers in MicrobiologyBackgroundMembers of the Burkholderia cepacia complex (Bcc) are known to cause severe pulmonary infections in immunocompromised hosts, namely individuals with cystic fibrosis (CF) and chronic granulomatous disease (CGD).
Antonio R. Mendez +3 more
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CT evaluation of the relationship between optic canal, anterior clinoid process, optic strut, caroticoclinoid foramen, and dimensions of sella turcica based on sphenoid sinus pneumatization patterns [PDF]
BMC Medical ImagingBackground Studies reported that sphenoid sinus pneumatization (SSP) affects paraclinoid structures, including the optic canal (OC), the anterior clinoid process (ACP), the optic strut (OS), and the sella turcica (ST).
Fatmanur İlgin +4 more
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Tumor-Targeted Cell-Penetrating Peptides Reveal That Monomethyl Auristatin E Temporally Modulates the Tumor Immune Microenvironment [PDF]
MoleculesChemotherapies remain standard therapy for cancers but have limited efficacy and cause significant side effects, highlighting the need for targeted approaches.
Mahsa Mortaja +11 more
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Campylobacter jejuni resistance to human milk involves the acyl carrier protein AcpP [PDF]
mBioCampylobacter jejuni is a common foodborne pathogen worldwide that is associated with high rates of morbidity and mortality among infants in low- to middle-income countries (LMICs).
Bibi Zhou +14 more
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SHAP-Based Identification of Potential Acoustic Biomarkers in Patients with Post-Thyroidectomy Voice Disorder [PDF]
DiagnosticsObjective: The objective of this study was to identify potential robust acoustic biomarkers for functional post-thyroidectomy voice disorder (PTVD) that may support early diagnosis and personalized treatment strategies, using acoustic analysis and ...
Salih Celepli +9 more
doaj +2 more sources
High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics [PDF]
Advanced ScienceAntimicrobial resistance is outpacing drug discovery, creating an urgent need for precision‐based strategies to counteract resistant pathogens. Peptide nucleic acid (PNA)‐based antisense molecules offer a promising approach by selectively inhibiting ...
Giorgia Danti +3 more
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Leptomeningeal Dissemination in Choroid Plexus Tumors: Magnetic Resonance Imaging Appearance and Risk Factors [PDF]
ChildrenBackground: Intracranial choroid plexus tumors (CPT) are rare and primarily affect young children. Leptomeningeal dissemination (LMD) has been reported not only in high-grade choroid plexus carcinoma (CPC) but also in lower histological grades; however ...
Daniel Nunes do Espirito Santo +13 more
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A Rare Case of Atypical Choroid Plexus Papilloma in an Adult Male Patient: A Case Report [PDF]
Case Reports in PathologyChoroid plexus tumors (CPTs) are rare neoplasms. Patient presentation varies depending on the location of the lesions. Gross total resection of primary lesions remains the gold standard for surgical treatment of CPTs.
Abebe Melis Nisiro +1 more
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A novel statistical feature selection framework for biomarker discovery and cancer classification via multiomics integration [PDF]
BMC Medical Research MethodologyBackground Early cancer diagnosis is essential for improving prognosis and guiding treatment. However, the high dimensionality and complexity of omics data present major challenges.
Moshira S. Ghaleb +3 more
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Frontiers in Cell and Developmental Biology, 2022 Deer antlers are male secondary sexual characters that develop to become bone; they are unique appendages that, once lost, can fully regenerate from the permanent bony protuberances or pedicles.
Qianqian Guo +7 more
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