Results 121 to 130 of about 4,624 (225)

ACRIDINE DERIVATIVES. PART V. AUROTHlO- AND ARGENTOTHIO-ACRIDINES.

, 1940
Gold and silver compounds of 5-thiolacridine derivatives have been described.
openaire   +1 more source

Effects of Acridines on Morphogenesis

Nature, 1968
EARLY studies of the effects of acridines on amphibian egg development tended to show that RNA synthesis is required for neural induction1. Little could be concluded from these experiments, however, because the acridines available at that time were a complex mixture of substances of unknown mode of action. Acridines have since been found to bind to and
openaire   +3 more sources

Synthesis, Properties, Applications and Challenges of Multicomponent Doped Organic Room Temperature Phosphorescence Materials

Aggregate, Volume 7, Issue 3, March 2026.
The multi‐component doping strategy, involving self‐assembly, host‐guest systems, and crystal engineering, has gained attention for its simplicity, cost‐effectiveness, structural diversity, and adjustable room‐temperature phosphorescence (RTP). This review summarizes and evaluates the progress in creating RTP materials using this strategy, highlighting
Zhenjie Zhou, Huizhong Wang, Junxiong Yao, Tian Wang, Jianhua Liu, Xiaohua Cao, Qiang Feng, Bingbing Yue, Dianyuan Wang, Jianguo Wang, Huanan Huang   +10 more
wiley   +1 more source

pH‐Responsive Sodium Alginate Micro‐Nano Hydrogels for Oral Insulin Delivery: Enhancing Therapeutic Efficacy and Reducing Hypoglycemic Risk

Food Frontiers, Volume 7, Issue 2, March 2026.
Schematic illustration of pH‐responsive SC@AP@INS for oral insulin delivery. (A) pH‐responsive mechanism of sodium alginate‐based hydrogels. (B) Preparation of drug‐loaded microsphere gel via the electrospray method. The controlled release of drug‐loaded micelles in the colon enhances insulin delivery efficiency while minimizing systemic exposure and ...
Minghui Kong, Haixia Yang, Daidi Fan, Jianjun Deng   +3 more
wiley   +1 more source

Synthesis, DNA binding studies of new pyrimidothiazepine and pyrimidobenzothiazepine derivatives [PDF]

, 2012
Several pyrimidothiazepine and pyrimidobenzothiazepine were synthesized starting from 6-chloro-1-methyluracil by the treatment with ethyl thioglycolate followed by the reaction with hydrazine hydrate which cyclized through refluxing with appropriate ...
Assy, Mohamed, Bayoumi, Ashraf, El-kalyoubi, Samar, Korraa, Makarem, Mousa, Bothaina   +4 more
core  

An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract

Journal of Applied Toxicology, Volume 46, Issue 3, Page 950-960, March 2026.
ABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
J. Kyle Weston, Barry S. Lynch, James A. Akingbasote   +2 more
wiley   +1 more source

Is Micronucleus Assay a Suitable Biomarker for Evaluating the Cancer Risk in Professionals Exposed to Antineoplastic Drugs? A Systematic Review

Journal of Applied Toxicology, Volume 46, Issue 3, Page 733-753, March 2026.
ABSTRACT The widespread use of antineoplastic drugs in cancer treatment has led to significant concerns regarding the potential health risks posed to healthcare professionals involved in the preparation, administration, and handling of these chemical compounds, including genotoxicity.
Thiago Guedes Pinto, Lorrany da Silva Avanci, Gabriel Carvalhal de Aguiar, Daniel Vitor de Souza, Patricia Ramos Cury, Ana Claudia Muniz Renno, Daniel Araki Ribeiro   +6 more
wiley   +1 more source

Complement Hyperactivation Is Mediated by Alternative and Lectin Pathways During Early Phase of Severe Vaccination‐Omicron BA.5 Infection

Journal of Medical Virology, Volume 98, Issue 3, March 2026.
ABSTRACT Complement temporal activation kinetics, activation pathways, and their relationship with thromboinflammation and antibody responses in severe vaccination‐COVID‐19 remains unclear. Based on a vaccinated‐infected cohort, we analyzed complement immune responses across mild to critical COVID‐19 cases by a dynamic model.
Jinpeng Cao, Gang Yang, Tingting Cui, Jian Qin, Deyi Huang, Shiqin Jin, Xiaoyun Yang, Mingzhu Huang, Xiaoling Su, Siyi Liu, Yingjiao Xia, Shidong Deng, Chengna Luo, Zhuxiang Zhao, Yunhui Zhang, Nanshan Zhong, Zhongfang Wang   +16 more
wiley   +1 more source

Phenothiazinium photoantimicrobials with basic side chains [PDF]

Derivatives of the standard cationic photosensitiser, methylene blue, were synthesised, having extra amino (basic) functionality in the auxochromic side-chain. The resulting analogues were profiled for photodynamic activity in vitro, and screened against
Ah, Ciara Loughran, Cincotta, Cincotta, Duan, Ehrlich, Gorman, Haberkorn, Henschler, Joanna Antczak, Katie Meegan, Margaron, Mark Wainwright, Martyna Baca, Mellish, Schulemann, Wainwright, Wainwright, Wainwright, Wainwright, Wainwright, Wainwright, Wainwright, Yin, Zirakzadeh   +24 more
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A Novel Peptide, HS1002, Enhances Antitumor Activity via Dual Targeting of the GnRH Receptor and Human Telomerase Reverse Transcriptase in Prostate Cancer Cells

MedComm, Volume 7, Issue 3, March 2026.
HS1002, a new peptide targeting GnRHR and hTERT, demonstrates significant Anticancer activity in prostate cancer cells. The mechanism of HS1002 can be attributed to the reduction of serum testosterone levels by desensitization of GnRHR, the downregulation of hTERT expression and telomerase activity, and the enhancement of Anticancer immunity.
Jae Hyeon Park, Joo Chan Lee, Swati Sharma, Chunxue Jiang, Haeun Lee, Hyun‐Ju Park, Hyung Sik Kim   +6 more
wiley   +1 more source