Results 21 to 30 of about 4,624 (225)
In the title compound, C23H24BrNO5, the central 1,4-dihydropyridine ring of the 1,2,3,4,5,6,7,8,9,10-decahydroacridine ring system adopts a half-chair conformation. The two cyclohexene rings fused to the central ring both have a twisted-boat conformation.
Shaaban K. Mohamed +5 more
doaj +1 more source
A Ce(IV)-catalyzed three-component reaction between chalcones, anilines and β-ketoesters followed by a microwave-assisted thermal cyclization afforded 1,3-diaryl-1,2-dihydroacridin-9(10H)-ones.
Damiano Rocchi +3 more
doaj +1 more source
Tricyclic Cationic Chromophores as Models for New Photoantimicrobials [PDF]
Despite the preponderance of literature pertaining to photosensitisers based on the porphyrin system, many other chemical classes are available with similar or improved characteristics and potential for use in photodynamic medicine.
Wainwright, M
core +1 more source
Relationships between the Mandibles, Feeding Behavior, and Damage Inflicted on Plants by the Feeding of Certain Acridids (Orthoptera) [PDF]
[excerpt] In 1960 the author described three fundamental patterns of feed- ing in Orthoptera and their allies and emphasized the close correlation that exists between the insects\u27 mouthpart structure, food, and feeding pattern. An article by Anderson (
Gangwere, S. K.
core +3 more sources
Synthesis, Biological Evaluation and Stability Studies of Some Novel Aza-Acridine Aminoderivatives
Several new amino-substituted aza-acridine derivatives bearing a basic side chain have been designed and synthesized. The antiproliferative activity of the target compounds has been evaluated against three cancer cell lines—namely HCT-116 (colorectal ...
Maria Karelou +7 more
doaj +1 more source
An Efficient Protocol for Synthesis of Pyrazolo[3,4-a]acridines [PDF]
A new class of pyrazolo[3,4-a]acridines have been prepared, the synthon acridones were obtained in very good yield by one pot reaction of 2-amino-5-chloro or nitro substituted benzophenones with 1,3-cyclic diketones in the presence of freshly prepared ...
Kaminsky, Werner +3 more
core +2 more sources
A small molecule that induces assembly of a four way DNA junction at low temperature [PDF]
Small molecules that induce the formation of higher order DNA structures have potential therapeutic and nanotechnology applications. Screening of a click library has identified the first compound to induce the formation of a Holliday junction structure ...
Bowater, RP +4 more
core +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
In the title compound, C27H32BrNO5, the central 1,4-dihydropyridine ring adopts a shallow sofa conformation (with the C atom bearing the bromophenol ring as the flap), whereas the pendant cyclohexene rings both have twisted-boat conformations.
Shaaban K. Mohamed +4 more
doaj +1 more source
C~3HsNC1, orthorhombic, P212~2 ~, a = 6.850 (3), b = 11.662 (5), c = 12.705 (5) A, O m = 1.40 (1), D c = 1.393 g cm -3 for Z = 4. Equi-inclination Weissenberg intensities, scanned with an automatic densitometer.
ACHARI, A, NEIDLE, S
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