Results 21 to 30 of about 4,624 (225)

Crystal structure of ethyl 2-[9-(5-bromo-2-hydroxyphenyl)-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydroacridin-10-yl]acetate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C23H24BrNO5, the central 1,4-dihydropyridine ring of the 1,2,3,4,5,6,7,8,9,10-decahydroacridine ring system adopts a half-chair conformation. The two cyclohexene rings fused to the central ring both have a twisted-boat conformation.
Shaaban K. Mohamed   +5 more
doaj   +1 more source

Sustainable Access to Acridin-9-(10H)ones with an Embedded m-Terphenyl Moiety Based on a Three-Component Reaction

open access: yesMolecules, 2020
A Ce(IV)-catalyzed three-component reaction between chalcones, anilines and β-ketoesters followed by a microwave-assisted thermal cyclization afforded 1,3-diaryl-1,2-dihydroacridin-9(10H)-ones.
Damiano Rocchi   +3 more
doaj   +1 more source

Tricyclic Cationic Chromophores as Models for New Photoantimicrobials [PDF]

open access: yes, 2015
Despite the preponderance of literature pertaining to photosensitisers based on the porphyrin system, many other chemical classes are available with similar or improved characteristics and potential for use in photodynamic medicine.
Wainwright, M
core   +1 more source

Relationships between the Mandibles, Feeding Behavior, and Damage Inflicted on Plants by the Feeding of Certain Acridids (Orthoptera) [PDF]

open access: yes, 2017
[excerpt] In 1960 the author described three fundamental patterns of feed- ing in Orthoptera and their allies and emphasized the close correlation that exists between the insects\u27 mouthpart structure, food, and feeding pattern. An article by Anderson (
Gangwere, S. K.
core   +3 more sources

Synthesis, Biological Evaluation and Stability Studies of Some Novel Aza-Acridine Aminoderivatives

open access: yesMolecules, 2020
Several new amino-substituted aza-acridine derivatives bearing a basic side chain have been designed and synthesized. The antiproliferative activity of the target compounds has been evaluated against three cancer cell lines—namely HCT-116 (colorectal ...
Maria Karelou   +7 more
doaj   +1 more source

An Efficient Protocol for Synthesis of Pyrazolo[3,4-a]acridines [PDF]

open access: yes, 2015
A new class of pyrazolo[3,4-a]acridines have been prepared, the synthon acridones were obtained in very good yield by one pot reaction of 2-amino-5-chloro or nitro substituted benzophenones with 1,3-cyclic diketones in the presence of freshly prepared ...
Kaminsky, Werner   +3 more
core   +2 more sources

A small molecule that induces assembly of a four way DNA junction at low temperature [PDF]

open access: yes, 2011
Small molecules that induce the formation of higher order DNA structures have potential therapeutic and nanotechnology applications. Screening of a click library has identified the first compound to induce the formation of a Holliday junction structure ...
Bowater, RP   +4 more
core   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie   +17 more
wiley   +1 more source

Ethyl 2-[9-(5-bromo-2-hydroxyphenyl)-3,3,6,6-tetramethyl-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydroacridin-10-yl]acetate

open access: yesIUCrData, 2017
In the title compound, C27H32BrNO5, the central 1,4-dihydropyridine ring adopts a shallow sofa conformation (with the C atom bearing the bromophenol ring as the flap), whereas the pendant cyclohexene rings both have twisted-boat conformations.
Shaaban K. Mohamed   +4 more
doaj   +1 more source

9-CHLOROACRIDINE [PDF]

open access: yes, 2002
C~3HsNC1, orthorhombic, P212~2 ~, a = 6.850 (3), b = 11.662 (5), c = 12.705 (5) A, O m = 1.40 (1), D c = 1.393 g cm -3 for Z = 4. Equi-inclination Weissenberg intensities, scanned with an automatic densitometer.
ACHARI, A, NEIDLE, S
core   +1 more source

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