Results 31 to 40 of about 4,641 (228)
, 2002 C~3HsNC1, orthorhombic, P212~2 ~, a = 6.850 (3), b = 11.662 (5), c = 12.705 (5) A, O m = 1.40 (1), D c = 1.393 g cm -3 for Z = 4. Equi-inclination Weissenberg intensities, scanned with an automatic densitometer.
ACHARI, A, NEIDLE, S
core +1 more source
Catalytic condensation for the formation of polycyclic heteroaromatic compounds
Nature Communications, 2018 The development of novel chemical reactions converting biomass-derived alcohols into important classes of compounds is a particularly attractive strategy.
Daniel Forberg +2 more
doaj +1 more source
Archaeometry, EarlyView., 2022 Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares +5 more
wiley +1 more source
Synthesis, characterization and antitumor activity of 2-methyl-9-substituted acridines [PDF]
, 2013 In the field of antitumor DNA-intercalating agents, 9-anilinoacridines play an important role due to their antiproliferative properties. Several cancer chemotherapeutics such as amascrine and nitracrine have been developed as anticancer agents.
Kumar, Rajesh +5 more
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Molecules, 2008 A series of 1-acyl-4-phenyl/(acridin-9-yl)thiosemicarbazides 3, including fournew compounds, were prepared in order to study substituent effects on cyclizationreactions with oxalyl chloride (producing imidazolidine-4,5-diones 4 ...
Karel D. Klika +7 more
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‘Acridines’ as New Horizons in Antifungal Treatment
Molecules, 2020 Frequent fungal infections in immunocompromised patients and mortality due to invasive mycosis are important clinical problems. Opportunistic pathogenic Candida species remain one of the leading causes of systemic mycosis worldwide.
Iwona Gabriel
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G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy [PDF]
, 2018 G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that form within guanine-rich strands of regulatory genomic regions. G4s have been extensively described in the human genome, especially in telomeres and oncogene promoters; in ...
Richter, Sara N, Ruggiero, Emanuela
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Düzce Tıp Fakültesi DergisiAim: This study aimed to synthesize a novel pyrazole acridine derivative (3-ACH) and evaluate its anticancer properties on SH-SY5Y human neuroblastoma cells.Material and Methods: The pyrazole-4-carbaldehyde derivative was cyclized with dimedone and p ...
Muna Elmusa +5 more
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A small molecule that induces assembly of a four way DNA junction at low temperature [PDF]
, 2011 Small molecules that induce the formation of higher order DNA structures have potential therapeutic and nanotechnology applications. Screening of a click library has identified the first compound to induce the formation of a Holliday junction structure ...
Bowater, RP +4 more
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Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound, C21H21NO5, crystallizes with two molecules in the asymmetric unit. In each molecule, the central 1,4-dihydropyridine ring adopts a shallow sofa conformations (with the C atom bearing the phenol ring as the flap), whereas the pendant ...
Mehmet Akkurt +5 more
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