Molecules, 2020 A Ce(IV)-catalyzed three-component reaction between chalcones, anilines and β-ketoesters followed by a microwave-assisted thermal cyclization afforded 1,3-diaryl-1,2-dihydroacridin-9(10H)-ones.
Damiano Rocchi +3 more
doaj +1 more source
A facile synthesis of N-H-and N-substituted acridine-1,8-diones under sonic condition [PDF]
, 2013 Synthesis of an assembly of structurally important N-H- and N-substituted acridine-1,8-diones by CAN (ceric ammonium nitrate) catalysed one-pot four-component reaction of electron-deficient and electron-rich aromatic aldehydes and aromatic amines or ...
Pasha, M.A., Sudha, S.
core +3 more sources
Tricyclic Cationic Chromophores as Models for New Photoantimicrobials [PDF]
, 2015 Despite the preponderance of literature pertaining to photosensitisers based on the porphyrin system, many other chemical classes are available with similar or improved characteristics and potential for use in photodynamic medicine.
Wainwright, M
core +1 more source
Synthesis, Biological Evaluation and Stability Studies of Some Novel Aza-Acridine Aminoderivatives
Molecules, 2020 Several new amino-substituted aza-acridine derivatives bearing a basic side chain have been designed and synthesized. The antiproliferative activity of the target compounds has been evaluated against three cancer cell lines—namely HCT-116 (colorectal ...
Maria Karelou +7 more
doaj +1 more source
Relationships between the Mandibles, Feeding Behavior, and Damage Inflicted on Plants by the Feeding of Certain Acridids (Orthoptera) [PDF]
, 2017 [excerpt] In 1960 the author described three fundamental patterns of feed- ing in Orthoptera and their allies and emphasized the close correlation that exists between the insects\u27 mouthpart structure, food, and feeding pattern. An article by Anderson (
Gangwere, S. K.
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An Efficient Protocol for Synthesis of Pyrazolo[3,4-a]acridines [PDF]
, 2015 A new class of pyrazolo[3,4-a]acridines have been prepared, the synthon acridones were obtained in very good yield by one pot reaction of 2-amino-5-chloro or nitro substituted benzophenones with 1,3-cyclic diketones in the presence of freshly prepared ...
Kaminsky, Werner +3 more
core +2 more sources
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
Hepatology, EarlyView., 2022 In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
IUCrData, 2017 In the title compound, C27H32BrNO5, the central 1,4-dihydropyridine ring adopts a shallow sofa conformation (with the C atom bearing the bromophenol ring as the flap), whereas the pendant cyclohexene rings both have twisted-boat conformations.
Shaaban K. Mohamed +4 more
doaj +1 more source
Stable σh-adducts in the reactions of the acridinium cation with heterocyclic N-nucleophiles [PDF]
, 2013 A reaction of NH-heterocycles with the 10-methylacridinium cation in the presence of a base led to 9,10-dihydro-10-methyl-9-substituted acridines, which can be considered as stable intermediates in the aromatic nucleophilic substitution reaction of ...
Budnikova, Y. G. +6 more
core +1 more source
Formation of a Unique Cluster of G-Quadruplex Structures in the HIV-1 nef Coding Region: Implications for Antiviral Activity [PDF]
, 2013 G-quadruplexes are tetraplex structures of nucleic acids that can form in G-rich sequences. Their presence and functional role have been established in telomeres, oncogene promoters and coding regions of the human chromosome.
Frasson, Ilaria +8 more
core +11 more sources