Results 21 to 30 of about 3,278 (246)
Acridine as an Anti-Tumour Agent: A Critical Review
Molecules, 2022 This review summarized the current breakthroughs in the chemistry of acridines as anti-cancer agents, including new structural and biologically active acridine attributes.
Potlapati Varakumar +9 more
doaj +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
Hepatology, EarlyView., 2022 In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
Molecules, 2001 Association constants of complexes of a new class of cyclodextrin alkyl derivatives - randomly susbstituted tert-butyl derivatives (TB-CDs) with complete set of mono-halobenzoic acids and acridine derivatives were measured using capillary electrophoresis
Josef Jůza +4 more
doaj +1 more source
Acta Crystallographica Section E Crystallographic Communications, 2019 We report a new polymorph of acridine, C13H9N, denoted form IX, obtained as thin needles by slow evaporation of a toluene solution. The structure was solved and refined from powder X-ray data. The structures of five unsolvated forms were previously known, but this is only the second with one molecule in the asymmetric unit.
Peter W. Stephens +3 more
openaire +3 more sources
Facile Synthesis of Unsymmetrical Acridines and Phenazines by a Rh(III)-Catalyzed Amination/Cyclization/Aromatization Cascade [PDF]
, 2013 We report formal [3 + 3] annulations of aromatic azides with aromatic imines and azobenzenes to give acridines and phenazines, respectively. These transformations proceed through a cascade process of Rh(III)-catalyzed amination followed by intramolecular
Jonathan A. Ellman +7 more
core +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C23H24BrNO5, the central 1,4-dihydropyridine ring of the 1,2,3,4,5,6,7,8,9,10-decahydroacridine ring system adopts a half-chair conformation. The two cyclohexene rings fused to the central ring both have a twisted-boat conformation.
Shaaban K. Mohamed +5 more
doaj +1 more source
Acta Crystallographica Section E Structure Reports Online, 2011 The title compound, C(13)H(9)N·0.75H(2)O was obtained during a study of the polymorphic system of acridine, by slow evaporation from an ethanol-water solution. There are two acridine mol-ecules (indicated by I and II, respectively) and one and a half water mol-ecules in the asymmetric unit.
Andreas Lemmerer +3 more
openaire +3 more sources
Acridine and Its Derivatives: Synthesis, Biological, and Anticorrosion Properties. [PDF]
Materials (Basel), 2022 The phenomenon of corrosion threatens metallic components, human safety, and the economy. Despite being eco-friendly and promising as a corrosion inhibitor, acridine has not been explored to its full potential.
Goni LKMO +3 more
europepmc +2 more sources
An Efficient Protocol for Synthesis of Pyrazolo[3,4-a]acridines [PDF]
, 2015 A new class of pyrazolo[3,4-a]acridines have been prepared, the synthon acridones were obtained in very good yield by one pot reaction of 2-amino-5-chloro or nitro substituted benzophenones with 1,3-cyclic diketones in the presence of freshly prepared ...
Rajendran, Satheeshkumar +3 more
core +1 more source
Molecules, 2020 A Ce(IV)-catalyzed three-component reaction between chalcones, anilines and β-ketoesters followed by a microwave-assisted thermal cyclization afforded 1,3-diaryl-1,2-dihydroacridin-9(10H)-ones.
Damiano Rocchi +3 more
doaj +1 more source