Results 51 to 60 of about 77,401 (163)

Antiparasitic activities of acridone alkaloids from Swinglea glutinosa (Bl.) Merr. [PDF]

, 2009
Onze alcalóides acridônicos isolados de Swinglea glutinosa (Bl.) Merr. foram avaliados para suas atividades in vitro contra linhagens de Plasmodium falciparum sensíveis a cloroquina 3D7, Trypanosoma brucei rhodesiense STIB9000 e Leishmania donovani L82 ...
Santos, Djalma AP dos, Croft, Simon L, Rattray, Lauren, Silva, M Fátima das GF da, Vieira, Paulo C, Fernandes, João B   +5 more
core   +1 more source

Mapping the Chemodiversity, Antioxidant and Enzyme Inhibitory Potential and In Silico Studies of Heliotropium europaeum

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
This study established a foundation for utilizing these results and compounds as drug leads ‐ for exploring the industrial applications of Heliotropium europaeum in developing products aimed at non‐communicable diseases. ABSTRACT The annual plant Heliotropium europaeum grows in waste ground next to agricultural land and along roadsides from June to ...
Shabnam Mustafa, Muhammad Imran Tousif, Naheed Raiz, Muhammad Saleem, Saba Tauseef, Gokhan Zengin, Laiba Hassan, Areeba Hassan, Mamona Nazir, Shabbir Muhammad   +9 more
wiley   +1 more source

Soil-borne microorganisms and soil-type affect pyrrolizidine alkaloids in Jacobaea vulgaris [PDF]

, 2009
Secondary metabolites like pyrrolizidine alkaloids (PAs) play a crucial part in plant defense. We studied the effects of soil-borne microorganisms and soil-type on pyrrolizidine alkaloids in roots and shoots of Jacobaea vulgaris.
Veen, J.A., van, Klinkhamer, P.G.L., Joosten, L., Mulder, P.P.J.   +3 more
core   +2 more sources

Glycomaurin and Glycomaurrol, New Carbazole Alkaloids From Glycosmis mauritiana (Rutaceae) Bark

, 1989
The stem bark of Glycosmis mauritiana contained the acridone alkaloids noracronycine and des-N- methylacronycine, and two new carbazole alkaloids, 3,3,10-trimethyl-3,7-dihydropyrano[2,3-c] carbazole (glycomaurin) and 6-methyl-4-(3′-methylbut-2′-enyl)
V Kumar, J Reisch, A Wickramasinghe
core   +1 more source

Indoloquinoline Alkaloids as Antimalarials: Advances, Challenges, and Opportunities

ChemMedChem, Volume 19, Issue 18, September 16, 2024.
Extracts from the plant C. sanguinolenta and the isolated indoloquinoline alkaloids have been found to possess potent antimalarial activities, in vitro and in vivo, against various strains of P. falciparum. Structure‐activity relationship studies identified more potent analogs.
Prakash T. Parvatkar, Khaly Diagne, Yingzhao Zhao, Roman Manetsch   +3 more
wiley   +1 more source

Anthranilate N-methyltransferase, a branch-point enzyme of acridone biosynthesis

, 2008
Acridone alkaloids formed by acridone synthase in Ruta graveolens L. are composed of N-methylanthraniloyl CoA and malonyl CoAs. A 1095 bp cDNA from elicited Ruta cells was expressed in Escherichia coli, and shown to encode S-adenosyl-l-methionine ...
Alfred Baumert, Hans, J, Martens, S, Stefan Martens, Joachim Hans, Hunziker, P, Rohde, B, Britta Rohde, Ulrich Matern, Peter Hunziker, Matern, U, Baumert, A   +11 more
core   +1 more source

Anti-protozoal activity of aporphine and protoberberine alkaloids from Annickia kummeriae (Engl. & Diels) Setten & Maas (Annonaceae) [PDF]

, 2013
BACKGROUND: Malaria, trypanosomiasis and leishmaniasis have an overwhelming impact in the poorest countries in the world due to their prevalence, virulence and drug resistance ability.
Swaleh, S. M., Hassanali, Ahmed, Ndiege, Isaiah O, Brun, R., Dalsgaard, Petur, Ahmed Hassanali, Ndiege, I. O., Malebo, Hamisi M, Monical Cal, Petur Dalsgaard, Maurice O Omolo, Hassanali, A., Wenzler, T., Sequin, U., Hamburger, M., Wenzler, Tanja, Tanja Wenzler, Omolo, M. O., Omolo, Maurice O, Hamisi M Malebo, Dalsgaard, P., Cal, M., Häussinger, Daniel, Daniel Häussinger, Häussinger, D., Hamburger, Matthias, Brun, Reto, Sauda M Swaleh, Malebo, H. M., Séquin, Urs, Isaiah O Ndiege, Reto Brun, Cal, Monical, Swaleh, Sauda M, Urs Séquin, Matthias Hamburger, Omolo, Maurice O., Ndiege, Isaiah O., Malebo, Hamisi M., Swaleh, Sauda M.   +39 more
core   +2 more sources

The Demethylation of Methoxyacridones

, 1952
4-Methoxy-10-methylacridone demethylates more readily than the 1-, 2-, or 3-isomers but not so readily as the acridone alkaloids. 4-Hydroxy-10-methylacridone resembles the nor-alkaloids but its isomers have distinctly different properties.
GK Hughes, AT Norman, E Ritchie, NK Matheson   +3 more
core   +1 more source

Alkaloids of glycosmis pentaphylla (Retz.) correa

, 1966
The isolation of skimmianine and three new acridone alkaloids from the root bark of Glycosmis pentaphylla (Retz.) correa is reported. Based on the spectral evidence and chemical correlations, these are shown to be hitherto naturally unknown noracronycine
B.R. Pai, Govindachari, T. R., P.S. Subramaniam, Pai, B. R., Subramaniam, P. S., T.R. Govindachari   +5 more
core   +1 more source

Marine pyridoacridine, pyridoacridone and pyrroloacridine alkaloids.

, 2023
The families of pyridoacridine, pyridoacridone, and pyrroloacridine alkaloids are fascinating classes of natural products that have attracted the attention of chemists for over 80 years.
Cadelis, Melissa M, Copp, Brent R
core   +1 more source