Results 31 to 40 of about 77,401 (163)

Pyridinoacridine alkaloids of marine origin: NMR and MS spectral data, synthesis, biosynthesis and biological activity

Beilstein Journal of Organic Chemistry, 2015
This review focuses on pyridoacridine-related metabolites as one biologically interesting group of alkaloids identified from marine sources. They are produced by marine sponges, ascidians and tunicates, and they are structurally comprised of four to ...
Louis P. Sandjo, Victor Kuete, Maique W. Biavatti   +2 more
doaj   +1 more source

The Ultraviolet Absorption Spectra of the Acridone Alkaloids. I. Compounds containing the Acridone Nucleus

, 1950
The ultraviolet spectra of the acridone alkaloids and some derivatives have been studied. The various bands in the spectra of these compounds are interpreted by starting with theoretical treatments of the spectrum of anthracene and tracing spectral ...
RD Brown, FN Lahey
core   +1 more source

New acridone alkaloids from Ugandan Vepris trichocarpa

Scientific African
Ugandan Vepris trichocarpa sampled for this study yielded two undescribed acridone alkaloids here named trichouganda A (1), a 2‑methoxy derivative of evoxanthine (2), and trichouganda B (4), a 6‑methoxy derivative of 1,3,5-trimethoxy-10-methyl acridone ...
Papin Mucaleque, Moses K. Langat, Eduard Mas-Claret, Martin Cheek, Iain Darbyshire   +4 more
doaj   +1 more source

Acridone alkaloids from Zanthoxylum zanthoxyloides exhibit in vitro anti-Candida, anti-biofilm and antifungal-resistance-modifying activities against drug-Resistant Candida albicans, Candida glabrata and other non-albicans Candida species

Results in Chemistry
Candida infections pose a growing global health threat, with high mortality rates driven by multidrug-resistant (MDR) strains, and a limited number of antifungals in the pipeline.
Benjamin Kingsley Harley, Maudesta Opoku, Theophilus Duku Asamoah, Angelina Efia Mantey, Inemesit Okon Ben, Jonathan Jato, Mike Okweesi Aggrey, Nii Korley Kortei, Theophilus Christian Fleischer   +8 more
doaj   +1 more source

Stereoretentive Nucleophilic Aromatic Substitution Accesses Atropisomeric 4‐Amino‐N‐Arylquinolinium Salts

Chemistry – A European Journal, Volume 32, Issue 37, 1 October 2026.
Quinolin‐4‐ones were converted to chloroquinolinium salts, allowing formation of axially chiral aminoquinolinium salts via an enantioretentive SNAr reaction with a variety of amine nucleophiles. The salts have a high rotational barrier, with a racemization half‐life of ∼1000s of years.
Darren Holmes, Nia Foster, Saima Ansari, Paul Kavanagh, Paul Dingwall, Peter C. Knipe   +5 more
wiley   +1 more source

The ultraviolet absorption spectra of the acridone alkaloids. II. Compounds related to 4–Quinolone

, 1950
A qualitative discussion, based mainly upon the MO approximation, is presented for the ultraviolet spectra of naphthalene, quinolone, and some degradation products of the acridone alkaloids related to 4 ...
RD Brown, Brown, R. D., Lahey, F. N., FN Lahey   +3 more
core   +1 more source

Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi

Angewandte Chemie, Volume 137, Issue 44, October 27, 2025.
Type III polyketide synthases (T3PKSs) produce diverse compounds of ecological and clinical importance. Here, the activity of 37 fungal T3PKSs was profiled, revealing unexpected products and generating several pharmaceutical precursors. The machine learning model trained on the activity data accurately extrapolates the predictions to other enzymes and ...
Nika Sokolova, Stepan S. Denisov, Thomas Hackl, Kristina Haslinger   +3 more
wiley   +2 more sources

Acridone Alkaloids and Coumarins from the Stem Bark of Citropsis articulata (Rutaceae)

, 2010
Meva'a LM, Songue JL, Wansi J, et al. Acridone Alkaloids and Coumarins from the Stem Bark of Citropsis articulata (Rutaceae). Zeitschrift für Naturforschung B.
Songue, Jules Lobe, Waffo, Alain Francois Kamdem, Etienne Dongo, Jules Lobe Songue, Norbert Sewald, Mpondo, Theophile Ngando, Sewald, Norbert ; https://orcid.org/, Jean Duplex Wansi, Dongo, Etienne, Alain Francois Kamdem Waffo, Wansi, Jean, Theophile Ngando Mpondo, Meva'a, Luc Mbaze, Luc Mbaze Meva'a   +13 more
core   +1 more source

Acridone alkaloids from the rhizomes of Luvunga scandens (Roxb.) Buch. Ham.

, 2018
The ethyl acetate extract of the rhizomes of Luvunga scandens (Roxb.) Buch. - Ham. ex Wight & Arn (Rutaceae) delivered one new acridone alkaloid named Luvungaside A (1) together with three known acridone alkaloids, namely 1,3-dihydroxy-2-methoxy-10 ...
Dinh Tri Mai (689087), Luu Hong Truong (3802102), Tan Phat Nguyen (689085), Thi Hong Tuoi Do (3703798), Minh Nhat Phan (5951270), Nguyen Kim Tuyen Pham (3118668), Nguyen Minh An Tran (5951267), Dung Tien Le (119213)   +7 more
core   +1 more source

Acridone alkaloids from Glycosmis chlorosperma as DYRK1A inhibitors

, 2014
Two new acridone alkaloids, chlorospermines A and B (1 and 2), were isolated from the stem bark of Glycosmis chlorosperma, together with the known atalaphyllidine (3) and acrifoline (4), by means of bioguided isolation using an in vitro enzyme assay ...
Lozach, O.B., Awang, K.D., Loaëc, N.B.C., Beniddir, M.A.A., Meijer, L.B.C., Iorga, B.L.A., Le Borgne, E.A., Litaudon, M.A.   +7 more
core   +3 more sources