Results 31 to 40 of about 2,769 (197)
2-Aminobenzaldehyde, a common precursor to acridines and acridones endowed with bioactivities
Tetrahedron, 2020 By starting from a common substrate, 2-aminobenzaldehyde, both acridines and acridones were prepared. The former were generated in high yields by copper-catalyzed N-arylation followed by acid-mediated cyclization while the latter were obtained by double ...
Sarah Zeghada +8 more
semanticscholar +1 more source
Natural acridones and coumarins as free radical scavengers: Mechanistic and kinetic studies
, 2020 In this work, we combined density functional theory (i.e., the M05-2X/6–311++G(d,p)//M05-2X/6–31+G(d) level) and statistical rate models to investigate free-radical scavenging activities of natural compounds found in Paramignya trimera root: four ...
T. C. Ngo +6 more
semanticscholar +1 more source
An Efficient Protocol for Synthesis of Pyrazolo[3,4-a]acridines [PDF]
, 2015 A new class of pyrazolo[3,4-a]acridines have been prepared, the synthon acridones were obtained in very good yield by one pot reaction of 2-amino-5-chloro or nitro substituted benzophenones with 1,3-cyclic diketones in the presence of freshly prepared ...
Kaminsky, Werner +3 more
core +2 more sources
Simple and non-charged long-lived fluorescent intracellular organelle trackers [PDF]
, 2020 In this work we evaluated by FLIM microscopy the preferential accumulation of long-lived acridone derivatives in mitochondria and lysosomes, based on a new concept of non-protonable and non-charged groups carriers. Thus, thiophene ring has been proved to
Cuerva Carvajal, Juan Manuel +9 more
core +1 more source
Methyltransferases from Ruta graveolens L.: Molecular Biology and Biochemistry [PDF]
, 2005 The common rue, Ruta graveolens L., is an aromatic plant. It contains acridone alkaloids, furoquinolines, coumarins, and numerous volatile compounds with antimicrobial and allelopathic activity.
Burga, Laura, Matern, Ulrich (Prof. Dr.)
core +1 more source
Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.A metallosupramolecular receptor binds squaraine dyes with high affinity and enables efficient dark resonance energy transfer (DRET) that generates bright near‐infrared emission with large pseudo‐Stokes shifts. ABSTRACT A metal‐organic cage was obtained by combining acridone‐based dipyridyl ligands with Pd2+ ions. The cage acts as a potent receptor for
Damien W. Chen +5 more
wiley +2 more sources
Synthesis, characterization and antitumor activity of 2-methyl-9-substituted acridines [PDF]
, 2013 In the field of antitumor DNA-intercalating agents, 9-anilinoacridines play an important role due to their antiproliferative properties. Several cancer chemotherapeutics such as amascrine and nitracrine have been developed as anticancer agents.
Kumar, Rajesh +5 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2019 Readily available 4-bromobenzo[c][2,7]naphthyridine undergoes regioselective direct ring metalation at C-5 with TMPMgCl∙LiCl at −40 °C. Quenching with various electrophiles gives a broad range of 5-substituted products, which are building blocks for the ...
Benedikt C. Melzer +2 more
doaj +1 more source
Anti-cancer activity of novel dibenzo[b,f]azepine tethered isoxazoline derivatives [PDF]
, 2012 10.1186/1472-6769-12-5BMC Chemical ...
Anilkumar, N.C. +10 more
core +3 more sources
Arylxanthones and arylacridones: a synthetic overview [PDF]
, 2016 Arylxanthones and arylacridones although not yet found in nature are becoming an important group of heterocyclic compounds due to their promising biological activities.
Pinto, Diana +3 more
core +1 more source