Results 51 to 60 of about 13,861 (172)

Healthcare utilization and costs among patients with acromegaly in the United States

Journal of Comparative Effectiveness Research
Aim: Recent evidence regarding the healthcare resource utilization (HCRU) and associated costs of acromegaly is limited. Materials & methods: This retrospective, cross-sectional administrative claims analysis (IQVIA Pharmetrics Plus) identified ...
Tiffany P Quock, Eunice Chang, Ashis K Das, Amanda Speller, Marian H Tarbox, Melinda L Rossi, Stacy K Rattana, Ingrid E Paulson, Michael S Broder   +8 more
doaj   +1 more source

Diagnostic challenges and management of a patient with acromegaly due to ectopic growth hormone-releasing hormone secretion from a bronchial carcinoid tumour

Endocrinology, Diabetes & Metabolism Case Reports, 2017
A male patient presented at the age of 30 with classic clinical features of acromegaly and was found to have elevated growth hormone levels, not suppressing during an oral glucose tolerance test.
Nikolaos Kyriakakis, Jacqueline Trouillas, Mary N Dang, Julie Lynch, Paul Belchetz, Márta Korbonits, Robert D Murray   +6 more
doaj   +1 more source

Saul Wilson Syndrome: A Case Report With New Features in Saudi Arabia

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Saul Wilson syndrome is an extremely rare genetic disorder caused by heterozygous de novo mutations in the COG4 gene. We report the first case from Saudi Arabia with previously unreported facial dysmorphic features, expanding the known phenotypic spectrum and emphasizing the importance of recognizing phenotypic variability in rare disorders.
Saad A. Bin Owaimer, Fatimah H. Abusrair, May R. Mutlaq, Eissa A. Faqeih, Leen Abu‐Safieh   +4 more
wiley   +1 more source

Clinical and economic burden among older adults with acromegaly in the United States

Journal of Comparative Effectiveness Research
Aim: To compare healthcare resource utilization (HCRU) and costs between older adults with and without acromegaly. Materials & methods: Using 2017–2022 100% Medicare Research Identifiable Files, we identified beneficiaries (≥65 years) with prevalent ...
Tiffany P Quock, Eunice Chang, Ashis K Das, Amanda Speller, Marian H Tarbox, Stacy K Rattana, Ingrid E Paulson, Michael S Broder   +7 more
doaj   +1 more source

Hip Structure Analyses in Acromegaly: Decrease of Cortical Bone Thickness After Treatment: A Longitudinal Cohort Study

JBMR Plus, 2019
Long‐standing growth hormone (GH) excess causes the skeletal clinical signs of acromegaly with typical changes in bone geometry, including increased cortical bone thickness (CBT).
Kristin Godang, Tove Lekva, Kjersti Ringvoll Normann, Nicoleta Cristina Olarescu, Kristin Astrid Berland Øystese, Anders Kolnes, Thor Ueland, Jens Bollerslev, Ansgar Heck   +8 more
doaj   +1 more source

Acromegaly and hypertension [PDF]

Jichu yixue yu linchuang, 2021
Acromegaly is usually caused by pituitary adenomas that secrete growth hormone (GH). The disease is prone to be complicated with hypertension and thus aggravates the state of the illness and increase the disease burden.
WANG Shu-chang, ZHU Hui-juan, PAN Hui
doaj  

Aneurysmal dilation of sinus of Valsalva in a patient with undiagnosed acromegaly

Clinical Case Reports, 2023
Key Clinical Message In patients presenting with aortic ectasia and myxomatous valve diseases at young ages, possible underlying acromegaly should be in mind. Abstract Acromegaly is a chronic systemic disease mainly caused by the benign pituitary adenoma
Hoda Gharoy, Sepideh Taghavi, Zahra Ghaemmaghami, Parham Rabiei, Azadeh Afzalnia   +4 more
doaj   +1 more source

Preoperative Metabolic Predictors of Granulation Subtypes in Somatotroph Tumors: A Multicenter Retrospective Cohort Study

CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
Somatotroph tumors, a rare subtype of pituitary adenomas, can be histologically classified into sparsely granulated (SGSTs) and densely granulated somatotroph tumors (DGSTs) based on cytokeratin staining. SGSTs are generally more invasive and less responsive to medical therapy, making their early identification clinically important.
Le Chen, Jiaming Wang, Ailiang Zeng, Farhana Akter, Shanshan Wang, Shitong Liu, Weiyu Hu, Shun Yao, Konstantinos Margetis, Zongming Wang, Haipeng Liu, Xin Wang   +11 more
wiley   +1 more source

Clinical and biochemical characteristics of patients with acromegaly and normal or increased prolactin levels

Alʹmanah Kliničeskoj Mediciny
Background: Prevalence of hyperprolactinemia in patients with acromegaly is 30 to 40%. Since recently, the necessity of screening for acromegaly in hyperprolactinemic patients with pituitary adenoma has been actively debated. The literature on this issue
Yuliya A. Kukushkina, Irena A. Ilovayskaya   +1 more
doaj   +1 more source

Keratinocyte‐Associated Biomarkers Reveal Pathogenic Mechanisms in Acne

FASEB BioAdvances, Volume 8, Issue 2, February 2026.
The study workflow integrates scRNA‐seq and bulk RNA‐seq data to characterize acne pathogenesis. Step 1 identifies expanded keratinocyte populations using single‐cell analysis. Step 2 filters candidate genes via WGCNA and differential expression integration.
Sini Cai, Yinjing Lin, Heng Xie, Xian Ao, Qiwei Liu, Lining Huang   +5 more
wiley   +1 more source