Results 111 to 120 of about 1,498,374 (404)
Silactins and Structural Diversity of Biosilica in Sponges
BiomimeticsSponges (phylum Porifera) were among the first metazoans on Earth, and represent a unique global source of highly structured and diverse biosilica that has been formed and tested over more than 800 million years of evolution. Poriferans are recognized as
Hermann Ehrlich +5 more
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Positioning of AMPA Receptor-Containing Endosomes Regulates Synapse Architecture
Cell Reports, 2015 Lateral diffusion in the membrane and endosomal trafficking both contribute to the addition and removal of AMPA receptors (AMPARs) at postsynaptic sites.
Marta Esteves da Silva +9 more
doaj +1 more source
Actin filament assembly by bacterial factors VopL/F: Which end is up? [PDF]
, 2017 Competing models have been proposed for actin filament nucleation by the bacterial proteins VopL/F. In this issue, Burke et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608104) use direct observation to demonstrate that VopL/F bind the barbed ...
Bosch +11 more
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
mBio, 2017 The intracellular bacterium Chlamydia trachomatis develops in a parasitic compartment called the inclusion. Posttranslationally modified microtubules encase the inclusion, controlling the positioning of Golgi complex fragments around the inclusion.
Jordan Wesolowski +8 more
doaj +1 more source
Cooperativity and Frustration in Protein-Mediated Parallel Actin Bundles
, 2009 We examine the mechanism of bundling of cytoskeletal actin filaments by two representative bundling proteins, fascin and espin. Small-angle X-ray studies show that increased binding from linkers drives a systematic \textit{overtwist} of actin filaments ...
B. Alberts +6 more
core +1 more source
ER-mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release. [PDF]
, 2017 The formin-like protein INF2 is an important player in the polymerization of actin filaments. In this issue, Chakrabarti et al. (2018. J. Cell Biol.
Koehler, Carla M, Steffen, Janos
core +1 more source
Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia [PDF]
, 2020 Rashmi Ranjan Das +2 more
openalex +1 more source
Journal of Cell Biology, 1986 A monoclonal antibody (anti-alpha sm-1) recognizing exclusively alpha- smooth muscle actin was selected and characterized after immunization of BALB/c mice with the NH2-terminal synthetic decapeptide of alpha- smooth muscle actin coupled to keyhole ...
Omar Skalli +3 more
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source