Results 61 to 70 of about 297,755 (331)

T lymphocyte migration: an action movie starring the actin and associated actors

open access: yesFrontiers in Immunology, 2015
The actin cytoskeleton is composed of a dynamic filament meshwork that builds the architecture of the cell to sustain its fundamental properties. This physical structure is characterized by a continuous remodeling, which allows cells to accomplish ...
Loïc eDupré   +4 more
doaj   +1 more source

Effects of post-translational modifications catalysed by pollen transglutaminase on the functional properties of microtubules and actin filaments [PDF]

open access: yes, 2009
TGases (transglutaminases) are a class of calcium-dependent enzymes that catalyse the interactions between acyl acceptor glutamyl residues and amine donors, potentially making crosslinks between proteins.
Bonner, PLR   +4 more
core  

Stress relaxation in F-actin solutions by severing

open access: yes, 2019
Networks of filamentous actin (F-actin) are important for the mechanics of most animal cells. These cytoskeletal networks are highly dynamic, with a variety of actin-associated proteins that control cross-linking, polymerization and force generation in ...
Arzash, S.   +4 more
core   +1 more source

Focal adhesions as mechanosensors: the two-spring model [PDF]

open access: yes, 2004
Adhesion-dependent cells actively sense the mechanical properties of their environment through mechanotransductory processes at focal adhesions, which are integrin-based contacts connecting the extracellular matrix to the cytoskeleton.
Schwarz, Ulrich S.   +2 more
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Effects of F/G-actin ratio and actin turn-over rate on NADPH oxidase activity in microglia

open access: yesBMC Immunology, 2010
Background Most in vivo studies that have addressed the role of actin dynamics in NADPH oxidase function in phagocytes have used toxins to modulate the polymerization state of actin and mostly effects on actin has been evaluated by end point measurements
Rasmussen Izabela   +5 more
doaj   +1 more source

Patterns in Space: Coordinating Adhesion and Actomyosin Contractility at E-cadherin Junctions

open access: yes, 2013
Cadherin adhesion receptors are fundamental determinants of tissue organization in health and disease. Increasingly, we have come to appreciate that classical cadherins exert their biological actions through active cooperation with the contractile actin ...
Wu, Selwin K., Yap, Alpha S.
core   +1 more source

Effect of omega-3 polyunsaturated fatty acids on the cytoskeleton: An open-label intervention study [PDF]

open access: yes, 2015
Background: Omega-3 polyunsaturated fatty acids (n-3 PUFAs) show beneficial effects on cardiovascular health and cognitive functions, but the underlying molecular mechanisms are not completely understood.
Hahn, Andreas   +5 more
core   +3 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Bending over backwards: BAR proteins and the actin cytoskeleton in mammalian receptor-mediated endocytosis

open access: yesEuropean Journal of Cell Biology, 2022
The role of the actin cytoskeleton during receptor-mediated endocytosis (RME) has been well characterized in yeast for many years. Only more recently has the interplay between the actin cytoskeleton and RME been extensively explored in mammalian cells ...
Garett Armstrong, Michael F. Olson
doaj  

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