Results 81 to 90 of about 316,202 (350)

Rheology at the micro-scale: new tools for bio-analysis [PDF]

, 2013
We present a simple and non-invasive experimental procedure to measure the linear viscoelastic properties of cells by passive particle tracking microrheology.
Carlsson, A., Cooper, J.M., Glidle, A., Li, X., Paterson, D.J., Tassieri, M., Warren, R.L.   +6 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

In vivo reorganization of the actin cytoskeleton in leaves of Nicotiana tabacum L. transformed with plastin-GFP. Correlation with light-activated chloroplast responses

BMC Plant Biology, 2009
Background The actin cytoskeleton is involved in the responses of plants to environmental signals. Actin bundles play the role of tracks in chloroplast movements activated by light.
Anielska-Mazur Anna, Bernaś Tytus, Gabryś Halina   +2 more
doaj   +1 more source

Porcine Colostrum Protects the IPEC-J2 Cells and Piglet Colon Epithelium against Clostridioides (syn. Clostridium) difficile Toxin-Induced Effects [PDF]

, 2020
Clostridioides difficile toxins are one of the main causative agents for the clinical symptoms observed during C. difficile infection in piglets. Porcine milk has been shown to strengthen the epithelial barrier function in the piglet’s intestine and may ...
Grześkowiak, Łukasz, Hauser, Anja E., Kröger, Susan, Martínez-Vallespín, Beatriz, Niesner, Raluca, Pieper, Robert, Vahjen, Wilfried, Zentek, Jürgen   +7 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Microvibration stimuli causes localized depolymerization of the actin cytoskeleton of osteoblasts around the nucleus

Journal of Biomechanical Science and Engineering
Reports have indicated that microvibration stimulation activates bone remodeling and promotes bone formation. However, the mechanism by which microvibration stimulation facilitates bone formation remains incompletely understood, and it is unclear how ...
Katsuya SATO, Satoshi ODA
doaj   +1 more source

Shielding of actin by the endoplasmic reticulum impacts nuclear positioning

Nature Communications, 2022
The nucleus connects to the actin cytoskeleton for nuclear movement in migrating cells. Here, the authors show that the endoplasmic reticulum shields actin cables to generate asymmetric nucleo-cytoskeleton connections for nuclear positioning.
Cátia Silva Janota, Andreia Pinto, Anna Pezzarossa, Pedro Machado, Judite Costa, Pedro Campinho, Cláudio A. Franco, Edgar R. Gomes   +7 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Actin Cytoskeleton: Formins Lead the Way [PDF]

Current Biology, 2004
Formins are eukaryotic proteins that potently influence actin polymerization dynamics. Recent evidence strongly suggests that these proteins move processively with the elongating barbed ends of actin filaments.
Harris, E.S, Higgs, H.N
openaire   +2 more sources

Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells [PDF]

, 2018
Imaging the actin cytoskeleton in cells uses a wide range of approaches. Typically, a fluorescent derivative of the small cyclic peptide phalloidin is used to image F-actin in fixed cells. Lifeact and F-tractin are popular for imaging the cytoskeleton in
A Nagasaki, AH Criddle, AJ Spracklen, AM Lengsfeld, B Visegrady, BJ Belin, C Ballestrem, C Ballestrem, C Tiede, C Xie, CW Lee, D Szczesna, E Behrmann, E Wulf, G Lukinavicius, H Aizawa, IN Rybakova, J Ecken von der, J Riedl, J Small, J Wehland, J Wehland, JI Robinson, K Sliogeryte, LD Belmont, M Fritzsche, M Melak, M Nemethova, MA Brehm, MA Michel, MJ Schell, NJ Haywood, SF Wulf, SM Heissler, T Oda, TD Pollard, YL Wang   +36 more
core   +2 more sources