Results 21 to 30 of about 243,847 (379)

Structure and function of Plasmodium actin II in the parasite mosquito stages.

open access: yesPLoS Pathogens, 2023
Actins are filament-forming, highly-conserved proteins in eukaryotes. They are involved in essential processes in the cytoplasm and also have nuclear functions.
Andrea J Lopez   +10 more
doaj   +1 more source

Cytoplasmic Beta and Gamma Actin Isoforms Reorganization and Regulation in Tumor Cells in Culture and Tissue

open access: yesFrontiers in Pharmacology, 2022
The cytoplasmic actin isoforms (β- and γ-actins) contribute greatly to cellular processes such as cel-cell and cell-matrix interactions, as well as cell polarization, motility and division. Distinct isoforms modulations are linked to serious pathologies,
V. B. Dugina   +3 more
doaj   +1 more source

Mechanism of deep-sea fish α-actin pressure tolerance investigated by molecular dynamics simulations.

open access: yesPLoS ONE, 2014
The pressure tolerance of monomeric α-actin proteins from the deep-sea fish Coryphaenoides armatus and C. yaquinae was compared to that of non-deep-sea fish C.
Nobuhiko Wakai   +3 more
doaj   +1 more source

Catastrophic disassembly of actin filaments via Mical-mediated oxidation. [PDF]

open access: yes, 2017
Actin filament assembly and disassembly are vital for cell functions. MICAL Redox enzymes are important post-translational effectors of actin that stereo-specifically oxidize actin's M44 and M47 residues to induce cellular F-actin disassembly.
Ge, Peng   +6 more
core   +3 more sources

Cytoplasmic actin is an extracellular insect immune factor which is secreted upon immune challenge and mediates phagocytosis and direct killing of bacteria, and is a Plasmodium Antagonist. [PDF]

open access: yesPLoS Pathogens, 2015
Actin is a highly versatile, abundant, and conserved protein, with functions in a variety of intracellular processes. Here, we describe a novel role for insect cytoplasmic actin as an extracellular pathogen recognition factor that mediates antibacterial ...
Simone L Sandiford   +5 more
doaj   +1 more source

Spectrins in Axonal Cytoskeletons: Dynamics Revealed by Extensions and Fluctuations [PDF]

open access: yes, 2014
The macroscopic properties, the properties of individual components and how those components interact with each other are three important aspects of a composited structure.
Carmo M.   +3 more
core   +1 more source

Localization of actin in Dictyostelium amebas by immunofluorescence [PDF]

open access: yes, 1977
Antibody prepared against avian smooth muscle actin has been used to localize actin in the slime mold, Dictyostelium discoideum. The distribution of actin in migrating cells is different from that in feeding cells.
Eckert, Barry S., Lazarides, Elias
core   +2 more sources

The Role of non-muscle actin paralogs in cell cycle progression and proliferation

open access: yesEuropean Journal of Cell Biology, 2023
Uncontrolled cell proliferation leads to several pathologies, including cancer. Thus, this process must be tightly regulated. The cell cycle accounts for cell proliferation, and its progression is coordinated with changes in cell shape, for which ...
Estera Jeruzalska, Antonina J. Mazur
doaj   +1 more source

The unusual dynamics of parasite actin result from isodesmic polymerization [PDF]

open access: yes, 2013
Previous reports have indicated that parasite actins are short and inherently unstable, despite being required for motility. Here, we re-examine the polymerization properties of actin in Toxoplasma gondii (TgACTI), unexpectedly finding that it exhibits ...
Cooper, John A   +6 more
core   +2 more sources

Actin and Actin-Binding Proteins [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2016
Organisms from all domains of life depend on filaments of the protein actin to provide structure and to support internal movements. Many eukaryotic cells use forces produced by actin polymerization for their motility, and myosin motor proteins use ATP hydrolysis to produce force on actin filaments.
openaire   +2 more sources

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