Results 21 to 30 of about 69,144 (145)

The actinome of Dictyostelium discoideum in comparison to actins and actin-related proteins from other organisms. [PDF]

open access: yesPLoS ONE, 2008
Actin belongs to the most abundant proteins in eukaryotic cells which harbor usually many conventional actin isoforms as well as actin-related proteins (Arps).
Jayabalan M Joseph   +8 more
doaj   +1 more source

Monoclonal antibodies against muscle actin isoforms: epitope identification and analysis of isoform expression by immunoblot and immunostaining in normal and regenerating skeletal muscle [version 2; referees: 3 approved]

open access: yesF1000Research, 2016
Higher vertebrates (mammals and birds) express six different highly conserved actin isoforms that can be classified in three subgroups: 1) sarcomeric actins, α-skeletal (α-SKA) and α-cardiac (α-CAA), 2) smooth muscle actins (SMAs), α-SMA and γ-SMA, and 3)
Christine Chaponnier, Giulio Gabbiani
doaj   +1 more source

Molecular characterization of three muscle alpha actin genes in mud loach (Misgurnus mizolepis; Cypriniformes)

open access: yesFisheries and Aquatic Sciences, 2017
Background Teleosts represent unique features in the regulation of muscle development and growth, with a great deal of myogenic plasticity. Muscle actins are major components to compose muscle fibers, and they play essential roles in cellular mobility ...
Sang Yoon Lee   +2 more
doaj   +1 more source

The mother of all actins?

open access: yeseLife, 2016
New insights into the structure of filaments made of crenactin, a homolog of actin found in archaea, shed light on how the cytoskeleton might have evolved.
Felipe Merino, Stefan Raunser
doaj   +1 more source

A method for rapidly screening functionality of actin mutants and tagged actins [PDF]

open access: yesBiological Procedures Online, 2004
Recombinant production and biochemical analysis of actin mutants has been hampered by the fact that actin has an absolute requirement for the eukaryotic chaperone CCT to reach its native state.
Rommelaere Heidi   +4 more
doaj   +1 more source

Divergent Plasmodium actin residues are essential for filament localization, mosquito salivary gland invasion and malaria transmission.

open access: yesPLoS Pathogens, 2022
Actin is one of the most conserved and ubiquitous proteins in eukaryotes. Its sequence has been highly conserved for its monomers to self-assemble into filaments that mediate essential cell functions such as trafficking, cell shape and motility.
Michelle Yee   +3 more
doaj   +1 more source

TNIK Regulates Cytoskeletal Organization to Promote Focal Adhesion Turnover and Mitosis in Lung Adenocarcinoma

open access: yesFrontiers in Bioscience-Landmark
Background: Lung cancer is the primary cause of cancer-related mortality, but the molecular mechanisms behind this malignancy remain unclear.
Yao Li   +9 more
doaj   +1 more source

Emerging Functions of Actins and Actin Binding Proteins in Trypanosomatids

open access: yesFrontiers in Cell and Developmental Biology, 2020
Actin is the major protein constituent of the cytoskeleton that performs wide range of cellular functions. It exists in monomeric and filamentous forms, dynamics of which is regulated by a large repertoire of actin binding proteins. However, not much was
Chhitar M. Gupta   +4 more
doaj   +1 more source

Conservation of conformational dynamics across prokaryotic actins.

open access: yesPLoS Computational Biology, 2019
The actin family of cytoskeletal proteins is essential to the physiology of virtually all archaea, bacteria, and eukaryotes. While X-ray crystallography and electron microscopy have revealed structural homologies among actin-family proteins, these ...
Natalie Ng   +3 more
doaj   +1 more source

The origins of phagocytosis and eukaryogenesis

open access: yesBiology Direct, 2009
Background Phagocytosis, that is, engulfment of large particles by eukaryotic cells, is found in diverse organisms and is often thought to be central to the very origin of the eukaryotic cell, in particular, for the acquisition of bacterial endosymbionts
Wolf Yuri I   +3 more
doaj   +1 more source

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