Results 41 to 50 of about 75,213 (335)
Computational prediction of actin–actin interaction [PDF]
Molecular Biology Reports, 2013 Actin is one of the most abundant proteins in eukaryotic cells, where it plays key roles in cell shape, motility, and regulation. Actin is found in globular (G) and filamentous (F) structure in the cell. The helix of actin occurs as a result of polymerization of monomeric G-actin molecules through sequential rowing, is called F-actin.
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Nature Reviews Genetics, 2018 Two independent studies now show that polymerization of branched actin at DNA double-strand breaks (DSBs) mediates chromatin dynamics associated with homology-directed repair and is required for a robust and error-free DSB repair process.
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Actin isoforms and neoplastic transformation
Успехи молекулярной онкологии, 2017 The cytoplasmic actins (β and γ) play crucial roles during key cellular processes like adhesion, migration, polarization and cytokinesis. The understanding of their specific underlying mechanisms would be of major relevance not only for fundamental ...
V. B. Dugina +3 more
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The unusual dynamics of parasite actin result from isodesmic polymerization [PDF]
, 2013 Previous reports have indicated that parasite actins are short and inherently unstable, despite being required for motility. Here, we re-examine the polymerization properties of actin in Toxoplasma gondii (TgACTI), unexpectedly finding that it exhibits ...
Cooper, John A +6 more
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F1000Research, 2016 Higher vertebrates express six different highly conserved actin isoforms that can be classified in three subgroups: 1) sarcomeric actins, α-skeletal (α-SKA) and α-cardiac (α-CAA), 2) smooth muscle actins (SMAs), α-SMA and γ-SMA, and 3) cytoplasmic actins
Christine Chaponnier, Giulio Gabbiani
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Relative importance of βcyto- and γcyto-actin in primary mouse embryonic fibroblasts [PDF]
, 2017 The highly homologous β (βcyto) and γ (γcyto) cytoplasmic actins are hypothesized to carry out both redundant and unique essential functions, but studies using targeted gene knockout and siRNA-mediated transcript knockdown to examine βcyto- and γcyto ...
Chamberlain, Christopher M. +5 more
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Stability domains of actin genes and genomic evolution
, 2007 In eukaryotic genes the protein coding sequence is split into several fragments, the exons, separated by non-coding DNA stretches, the introns. Prokaryotes do not have introns in their genome.
A. Dkhissi +9 more
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, 2014 Collective dynamics and force generation by cytoskeletal filaments are crucial in many cellular processes. Investigating growth dynamics of a bundle of N independent cytoskeletal filaments pushing against a wall, we show that chemical switching (ATP/GTP ...
Das, Dibyendu +2 more
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Septin filament organization in Saccharomyces cerevisiae. [PDF]
, 2012 Septins are a family of GTP-binding, membrane-interacting cytoskeletal proteins, highly conserved and essential in all eukaryotes (with the exception of plants). Septins play important roles in a number of cellular events that involve membrane remodeling
Bertin, Aurélie, NOGALES, Eva
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Mechanisms of Development, 2003 1. From molecules to morphologyMetazoan development is often viewed as a series ofinformation processing events in which the genomecomputes where and when to synthesize particular geneproducts. Importantly, development is also a feat ofengineering in which genetic information is used to changecell shape and cell–cell interactions to generate form ...
Buzz Baum, António Jacinto
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