Results 261 to 270 of about 472,934 (298)

Transcriptional and epigenetic regulation of autophagy: mechanisms, disease relevance and therapeutic opportunities. [PDF]

Signal Transduct Target Ther
Seo J, Park SY, Lee DC, Yoo W, Yang YR, Seo HW, Park JL, Joo JY, Park KC, Byun S.   +9 more
europepmc   +1 more source

Molecular Mechanisms of Cadmium-Induced Apoptosis in Fish Cells: A Review. [PDF]

Int J Mol Sci
Dai Y, Guo Y, Wang D, Luo W, Zou J, Du Z.   +5 more
europepmc   +1 more source

Neointimal hyperplasia and vascular restenosis: from molecular mechanisms to therapeutic interventions. [PDF]

Mol Biomed
Yi L, Chen T, Zhou Y, Zhu P, Zhu Q, Shao Y, Yao W.   +6 more
europepmc   +1 more source

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Levels of activating transcription factor 6 alpha (ATF6α) in Alzheimer’s disease

Alzheimer's & Dementia, 2023
AbstractBackgroundAlzheimer’s disease (AD) is the most prevalent neurodegenerative disease worldwide. More than 40 million people currently suffer from AD, and such prevalence tends to increase considerably in the coming decades due to increased human longevity.
Mariana Gomes Chauvet, Alinny Rosendo Isaac, Sergio T. Ferreira, Mychael V. Lourenco   +3 more
openaire   +1 more source

Transcriptional Activation of the Factor VIII Gene in Liver Cell Lines by Interleukin-6

Thrombosis and Haemostasis, 1998
SummaryCirculating factor VIII (fVIII) levels increase during inflammation suggesting that fVIII synthesis or secretion is stimulated during acute inflammation. To examine the mechanisms underlying this increase in circulating factor VIII, we have developed a sensitive and reliable semi-quantitative assay for fVIII mRNA utilising competitive reverse ...
D, Stirling, W A, Hannant, C A, Ludlam
openaire   +2 more sources

The significance of the activating transcription factor 6 gene in the pathogenesis of drug resistant cancer

Tissue and Cell
Chemotherapy remains a cornerstone in cancer therapy, but its effectiveness is often hindered by the development of drug resistance, a significant factor contributing to over 90 % of cancer-related deaths worldwide. A critical aspect of this resistance involves chronic endoplasmic reticulum stress, which activates the unfolded protein response (UPR ...
Ashkan, Khanishayan, Soheila, Rahgozar, Diba, Zebardast   +2 more
openaire   +2 more sources

Transcription factor GATA-6 activates expression of gastroprotective trefoil genes TFF1 and TFF2

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 2000
One of the early events in inflammation and epithelial restitution of the gastrointestinal tract is the up-regulation of secretory peptides belonging to the trefoil factor family (TFF) that promote cell migration, protect and heal the mucosa. Their major expression site is stomach (TFF1, TFF2) and intestine (TFF3).
E D, Al-azzeh, P, Fegert, N, Blin, P, Gött   +3 more
openaire   +2 more sources