Results 1 to 10 of about 54,274 (285)
Acyclovir-Loaded Solid Lipid Nanoparticles: Optimization, Characterization and Evaluation of Its Pharmacokinetic Profile [PDF]
Nanomaterials, 2020 Acyclovir is an antiviral drug used for the treatment of herpes simplex virus infection. Its oral bioavailability is low; therefore, frequent and high doses are prescribed for optimum therapeutic efficacy.
Haniza Hassan +6 more
doaj +2 more sources
Pharmaceutics, 2018 Acyclovir is not a good candidate for passive permeation since its polarity and solubility limit is partitioning into the stratum corneum. This work aims to develop a new topical formulation for the acyclovir delivery.
Manuela Donalisio +2 more
exaly +3 more sources
Two cases of a pharmacokinetic interaction between (val)acyclovir and mycophenolate mofetil
Clinical Infection in Practice, 2023 Background: Administration of (val)acyclovir in combination with mycophenolate mofetil (MMF) can result in increased acyclovir plasma levels due to competition with acyclovir for renal tubular secretion.
F.A. Berger +2 more
doaj +1 more source
Effectiveness of acyclovir in the treatment of pityriasis rosea. A systematic review and meta-analysis [PDF]
Anais Brasileiros de Dermatologia, 2018 : Background: There is a lack of evidence to support acyclovir administration in pityriasis rosea. Objective: To determine the efficacy of acyclovir in patients with typical pityriasis rosea.
Milton Rodriguez-Zuniga +2 more
doaj +1 more source
Acyclovir-induced glomerulonephritis in a 40-year-old woman without medical history: a case report
European Journal of Case Reports in Internal Medicine, 2023 Well-known side effects of acyclovir are nephrotoxicity and neurotoxicity. We present a 49-year-old woman without pre-existing renal failure, with an acute kidney injury and encephalopathy. Since there was a clear correlation with the intake of acyclovir
Marie-Justine Desrumaux +2 more
doaj +1 more source
Saudi Pharmaceutical Journal, 2022 Objectives: Acyclovir is approved to treat herpes simplex virus (HSV) type 1, type 2 and varicella-zoster virus. It is mainly eliminated via the kidneys, for which drug crystals accumulation might lead to nephrotoxicity. This study aimed to determine the
Abdullah M. Al-Alawi +4 more
doaj +1 more source
Acyclovir crystalluria: The utility of bedside urine routine microscopic examination
Journal of Pediatric Critical Care, 2020 Acyclovir, an acyclic nucleoside, is commonly used for the treatment of viral infections. Acyclovir is well tolerated in children. However, severe nephrotoxicity has been shown to occur in some children.
Puneet Jain +3 more
doaj +1 more source
IN VITRO COMPARATIVE OF DIFFERENT ACYCLOVIR TABLET [PDF]
Basrah Journal of Veterinary Research, 2012 The aim of the study was to compare the in vitro performance of different acyclovir tablets of the same strength from different companies under different trade names: Acyclovir actavis 400mg tab ,Acic 400mg tab ,and Veramide 400mg tab., and compare with ...
Nadheerah Falih Neamah
doaj +1 more source
Evaluation of the effects of acyclovir and/or human amniotic membrane on herpes virus culture and quantitative virus inactivity by real-time polymerase chain reaction [PDF]
International Journal of Ophthalmology, 2014 AIM: To investigate the permeability of amniotic membrane in herpes virus cell culture to acyclovir with real time polymerase chain reaction (RT-PCR).METHODS: Madin-Darby Bovine Kidney (MDBK) cell culture and Bovine Herpes Virus (BHV1) type 1 were used ...
Feride Aylin Kantarci +3 more
doaj +1 more source
Acyclovir induced hypokalemia [PDF]
Journal of Clinical Virology, 2013 Intravenous (IV) acyclovir, a mainstay antiviral for herpesviruses, may cause crystalluria and lead to acute kidney injury.1 Acyclovir has been associated with lower levels of potassium in canines but acyclovir induced hypokalemia has been reported only once in humans as part of a large adverse drug reaction monitoring program.2,3 A patient with a ...
Paul E, Drawz +2 more
openaire +2 more sources