Results 1 to 10 of about 27,547 (176)

Therapeutic Impact of Caffeic Acid Phenethyl Ester and Acyclovir Combination on Human Gingival Fibroblasts (HGF-1) Infected With Herpes Simplex Type 1 ICP0. [PDF]

Microbiologyopen
ABSTRACT Herpes simplex virus Type 1 (HSV‐1) is a prevalent infectious agent globally, often causing oral infections like gingivostomatitis. The ICP0 protein of HSV‐1 exacerbates infection severity by inhibiting antiviral responses. Our study explored how combinations of CAPE (caffeic acid phenethyl ester) and acyclovir influenced immune responses in ...
Sen M, Celik S.
europepmc   +2 more sources

CMV Preventive and Treatment Studies in Children Undergoing Haematopoietic Stem Cell Transplant: A Systematic Review. [PDF]

Rev Med Virol
ABSTRACT Cytomegalovirus (CMV) is one of the most important infectious causes of morbidity and mortality in children undergoing haematopoietic stem cell transplant (HSCT). However, the evidence for preventing and treating CMV disease in children in this context remains limited. We sought to review the current available evidence regarding the prevention
Fusani L, Fusco E, Fonseca M, Breuer J, Rao K, Galli L, Bamford A, Kadambari S.   +7 more
europepmc   +2 more sources

Sequential Varicella and Herpes Zoster in an Immunocompetent Adult. [PDF]

Clin Case Rep
ABSTRACT Varicella and herpes zoster, caused by primary infection and reactivation of varicella‐zoster virus (VZV) respectively, can present with a wide spectrum of cutaneous and systemic complications. This case highlights an uncommon sequential presentation of varicella and zoster in an immunocompetent adult in noncontiguous dermatomes and emphasizes
Sharma B, Paudel S.
europepmc   +2 more sources

Two cases of a pharmacokinetic interaction between (val)acyclovir and mycophenolate mofetil

Clinical Infection in Practice, 2023
Background: Administration of (val)acyclovir in combination with mycophenolate mofetil (MMF) can result in increased acyclovir plasma levels due to competition with acyclovir for renal tubular secretion.
F.A. Berger, J.E. Nagtegaal, M.M. Malingré   +2 more
doaj   +1 more source

Effectiveness of acyclovir in the treatment of pityriasis rosea. A systematic review and meta-analysis [PDF]

Anais Brasileiros de Dermatologia, 2018
: Background: There is a lack of evidence to support acyclovir administration in pityriasis rosea. Objective: To determine the efficacy of acyclovir in patients with typical pityriasis rosea.
Milton Rodriguez-Zuniga, Natalie Torres, Herney Garcia-Perdomo   +2 more
doaj   +1 more source

Acyclovir-induced glomerulonephritis in a 40-year-old woman without medical history: a case report

European Journal of Case Reports in Internal Medicine, 2023
Well-known side effects of acyclovir are nephrotoxicity and neurotoxicity. We present a 49-year-old woman without pre-existing renal failure, with an acute kidney injury and encephalopathy. Since there was a clear correlation with the intake of acyclovir
Marie-Justine Desrumaux, Elien Mahieu, Céline Vanfraechem   +2 more
doaj   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Incidence, patterns, risk factors and clinical outcomes of intravenous acyclovir induced nephrotoxicity

Saudi Pharmaceutical Journal, 2022
Objectives: Acyclovir is approved to treat herpes simplex virus (HSV) type 1, type 2 and varicella-zoster virus. It is mainly eliminated via the kidneys, for which drug crystals accumulation might lead to nephrotoxicity. This study aimed to determine the
Abdullah M. Al-Alawi, Juhaina Salim Al-Maqbali, Maria Al-Adawi, Anan Al-Jabri, Henrik Falhammar   +4 more
doaj   +1 more source

Acyclovir crystalluria: The utility of bedside urine routine microscopic examination

Journal of Pediatric Critical Care, 2020
Acyclovir, an acyclic nucleoside, is commonly used for the treatment of viral infections. Acyclovir is well tolerated in children. However, severe nephrotoxicity has been shown to occur in some children.
Puneet Jain, Ramachandran Rameshkumar, Ponnarmeni Satheesh, Subramanian Mahadevan   +3 more
doaj   +1 more source

IN VITRO COMPARATIVE OF DIFFERENT ACYCLOVIR TABLET [PDF]

Basrah Journal of Veterinary Research, 2012
The aim of the study was to compare the in vitro performance of different acyclovir tablets of the same strength from different companies under different trade names: Acyclovir actavis 400mg tab ,Acic 400mg tab ,and Veramide 400mg tab., and compare with ...
Nadheerah Falih Neamah
doaj   +1 more source