Results 91 to 100 of about 51,515 (263)
Mass Spectrometry Reviews, EarlyView.ABSTRACT Phytocannabinoids are bioactive metabolites derived from the Cannabis sativa plant. They have garnered attention due to their recreational uses and therapeutic potential. Although various analytical strategies have been employed for their analysis, mass spectrometry (MS) coupled to chromatographic separation is superior due to its sensitivity ...
Radwa Mahmoud +2 more
wiley +1 more source
PharmaceuticalsMetabolic syndrome (MetS) comprises a cluster of metabolic risk factors, which include obesity, hypertriglyceridemia, high blood pressure, and insulin resistance.
Angélica Sofía González-Garibay +5 more
doaj +1 more source
FeCl3‐Catalyzed Synthesis of Ynones from Silylated Alkynes and Acetic Anhydride
ChemistryOpen, EarlyView.The synthesis of alkynones from silylated alkynes and acid chlorides, first reported by Birkhofer in 1963, remains a valuable transformation. However, its reliance on stoichiometric AlCl3 and corrosive reagents raises environmental and practical concerns. To address this, a greener protocol using catalytic FeCl3 and acetic anhydride is developed.
Paul Charki +2 more
wiley +1 more source
Recent Developments in Photoinduced Decarboxylative Acylation of α-Keto Acids
MoleculesKetones are ubiquitous patterns found in various biological molecules and natural products. In recent years, a number of acylation methods have been developed based on the use of α-oxocarboxylic acids as acyl-transfer reagents, with particular emphasis ...
Shuaiqi Lu +3 more
doaj +1 more source
Tuning adsorption and morphology in poly(glutamic acid) via controlled acidic partial deprotection
Polymer International, EarlyView.Partial deprotection of poly(glutamic acid) generates morphologies and assemblies that match fully deprotected polypeptides in small‐molecule adsorption, extending to block copolypeptides with pH‐dependent effects. Abstract Synthetic polypeptides prepared from N‐carboxyanhydride (NCA) monomers are important platforms for environmental and medical ...
Hunter Wood +5 more
wiley +1 more source
PROTEOMICS, EarlyView.ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim +4 more
wiley +1 more source
Specificity of fatty acid acylation of cellular proteins.
, 1985 Eric N. Olson +2 more
openalex +1 more source
Discovery of Novel Small Molecule Anti-HCV Agents via the CypA Inhibitory Mechanism Using O-Acylation-Directed Lead Optimization [PDF]
, 2015 Wenzhong Yan +9 more
openalex +1 more source
The continuing significance of chiral agrochemicals
Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source