Results 101 to 110 of about 126,317 (283)
Proofreading of Noncognate Acyl Adenylates by an Acyl-Coenzyme A Ligase
Chemistry & Biology, 2013 Aminoacyl-tRNA synthetases remove (proofread) incorrect substrates and thereby prevent errors in protein synthesis. We report enzyme-catalyzed pretransfer editing by pimeloyl-coenzyme A (CoA) ligase (BioW), a biotin synthetic enzyme that converts pimelate, a seven-carbon dicarboxylic acid, to its CoA ester.
Manandhar, Miglena, Cronan, John E.
openaire +2 more sources
Chemistry – A European Journal, EarlyView.This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami +2 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato +3 more
wiley +1 more source
Precision Chemistry for Protein Lysine Modification
Chemistry – A European Journal, EarlyView.Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
Enzymatic synthesis of acyl‐acyl carrier protein and assay of acyl carrier protein [PDF]
FEBS Letters, 1979 Spencer, Allen K. +2 more
openaire +2 more sources
Mechanochemical Hydrodeoxygenations
European Journal of Organic Chemistry, EarlyView.A silver‐catalyzed mechanochemical hydrodeoxygenation with triethylsilane as reductant allows to convert ketones to the corresponding methylene derivatives in good yields after a short reaction time. Selected examples show that also alcohols, ethers, and sulfoxides can react. In this work, a mechanochemical hydrodeoxygenation (HDO) was developed. Using
Lena M. Hanek, Carsten Bolm
wiley +1 more source
Emerging Trends in Organic Photoreactions Utilizing Disulfides
European Journal of Organic Chemistry, EarlyView.Disulfides are versatile, nontoxic alternatives to metal photocatalysts. This review explores their role as photoactivated thiyl‐radical precursors and bifunctional catalysts (HAT/electron shuttling) in diverse transformations. Strategies for electronic tuning and development into recyclable heterogeneous materials are highlighted for sustainable ...
Sunil Kumar +3 more
wiley +1 more source
Remarkable Formation of Indene Derivatives Upon Friedel–Crafts Acylation Reactions
European Journal of Organic Chemistry, EarlyView.This shows indene derivatives. Under the reaction conditions of a Friedel–Crafts acylation, alkyl benzenes underwent an unprecedented cyclopentannulation furnishing indene derivatives. Alkylbenzene derivatives react with two equivalents of pivaloyl chloride (PivCl) in the presence of aluminum trichloride under formation of indene derivatives with up to
Leah Bantel +3 more
wiley +1 more source
Food Chemistry International, EarlyView.ABSTRACT The growing global demand for sustainable, nutritionally balanced protein sources has intensified interest in plant‐derived proteins, particularly those derived from oilseeds such as groundnut (Arachis hypogaea L.). However, although groundnut protein isolates (GPIs) have high nutritional quality, they exhibit limitations in technofunctional ...
Ángel Efraín Rodríguez Rivera +6 more
wiley +1 more source
Surface intermediate species of the 4-isobutylacetophenone adsorption-reaction over fosfotungstic Wells-Dawson heteropoly acid [PDF]
, 2009 Surface adsorbed species of isobutylbenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid have been screened in the present investigation.
Briand, Laura Estefania +2 more
core +1 more source